Beatrice Mercorelli

University of Padua — Italy

Medicine · Health Sciences

25h-index2.0kcitations52works7.82yr avg
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Research Topics

Cytomegalovirus and herpesvirus research(25), Herpesvirus Infections and Treatments(16), Influenza Virus Research Studies(12), HIV Research and Treatment(10), RNA and protein synthesis mechanisms(8)

Publications52 total

Discovery of a tetrahydrobenzothiophen-2-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide-based PROTAC as degrader of SARS-CoV-2 Main Protease
European Journal of Medicinal Chemistry·2026
Letermovir shows antiviral and neuroprotective effects in differentiating neurons and cerebral organoids mimicking human developing brain
Cellular and Molecular Life Sciences·2026Open Access
New dengue virus inhibitors targeting NS3-NS5 interaction identified by in silico screening
Frontiers in Microbiology·2025Open Access
Antiviral drug repurposing: different approaches and the case of antifungal drugs
Pharmacology & Therapeutics·2025· 2 cited
Novel SARS-CoV-2 allosteric inhibitors that destabilize the Main Protease Mpro dimer
International Journal of Biological Macromolecules·2025· 2 citedOpen Access
Antiviral strategies against influenza virus: an update on approved and innovative therapeutic approaches
Cellular and Molecular Life Sciences·2025· 30 citedOpen Access
PROteolysis TArgeting Chimeras (PROTACs) and beyond: targeted degradation as a new path to fight microbial pathogens
FEMS Microbiology Reviews·2025· 3 citedOpen Access
Synergistic activity of an RNA polymerase PA-PB1 interaction inhibitor with oseltamivir against human and avian influenza viruses in cell culture and in ovo
Antiviral Research·2024· 4 citedOpen Access
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization
European Journal of Medicinal Chemistry·2024· 6 citedOpen Access
Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity
European Journal of Medicinal Chemistry·2024· 33 citedOpen Access
Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus inhibitors
Antiviral Research·2024· 6 citedOpen Access
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability
Journal of Medicinal Chemistry·2023· 26 citedOpen Access
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells
Cancer Letters·2023· 19 citedOpen Access
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy <i>In Vivo</i>
mBio·2023· 20 citedOpen Access
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization
Antiviral Research·2022· 20 citedOpen Access
Targeted Disruption of E6/p53 Binding Exerts Broad Activity and Synergism with Paclitaxel and Topotecan against HPV-Transformed Cancer Cells
Cancers·2021· 18 citedOpen Access
Repurposing Approved Drugs to Block Highly Pathogenic Emerging Viruses
2021
Indomethacin-based PROTACs as pan-coronavirus antiviral agents
European Journal of Medicinal Chemistry·2021· 87 citedOpen Access
The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib
Cancers·2021· 14 citedOpen Access
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication
Viruses·2021· 4 citedOpen Access
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Frequent Co-authors

Arianna Loregian(48), Giorgio Palù(33), Marta Celegato(11), Giulia Muratore(10), Laura Goracci(10), Oriana Tabarrini(10), Gabriele Cruciani(9), Giorgio Gribaudo(9), Giulio Nannetti(8), Serena Massari(8), Elisa Sinigalia(7), Lorenzo Messa(7), Chiara Bertagnin(7), Anna Luganini(7), Jenny Desantis(6), Violetta Cecchetti(6), Gualtiero Alvisi(6), Alessandro Bazzacco(5), Stefano Sabatini(4), Michela Eleuteri(3)