Luke K. Burke

AstraZeneca (United Kingdom) — United Kingdom

Neuroscience · Life Sciences

14h-index1.1kcitations18works16.02yr avg
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Research Topics

Regulation of Appetite and Obesity(15), Biochemical Analysis and Sensing Techniques(6), Adipose Tissue and Metabolism(5), Neuropeptides and Animal Physiology(4), Circadian rhythm and melatonin(3)

Publications18 total

Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Across Multiple Clinically Relevant Subgroups in the NAVIGATOR Study
Advances in Therapy·2024· 16 citedOpen Access
Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells
Endocrinology·2020· 60 citedOpen Access
Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake
Cell Metabolism·2018· 143 citedOpen Access
MEDI0382, a GLP-1/Glucagon Receptor Dual Agonist, Shows Differential Brain Activation vs. Liraglutide in Mice
Diabetes·2018
Lorcaserin improves glycemic control via a melanocortin neurocircuit
Molecular Metabolism·2017· 61 citedOpen Access
mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice
eLife·2017· 52 citedOpen Access
mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice
2017Open Access
Author response: mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice
2017Open Access
Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite
Molecular Brain·2016· 51 citedOpen Access
Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit
eLife·2016· 191 citedOpen Access
Author response: Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit
2016· 2 citedOpen Access
Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons
Molecular Metabolism·2016· 86 citedOpen Access
5‐Hydroxytryptamine Medications for the Treatment of Obesity
Journal of Neuroendocrinology·2015· 78 cited
A Parabrachial-Hypothalamic Cholecystokinin Neurocircuit Controls Counterregulatory Responses to Hypoglycemia
Cell Metabolism·2014· 167 citedOpen Access
5-HT Obesity Medication Efficacy via POMC Activation is Maintained During Aging
Endocrinology·2014· 50 citedOpen Access
Distribution of cells responsive to 5-HT6 receptor antagonist-induced hypophagia
Behavioural Brain Research·2014· 32 citedOpen Access
Melanocortin‐3 receptors are involved in adaptation to restricted feeding
Genes Brain & Behavior·2012· 52 citedOpen Access
Food images engage subliminal motivation to seek food
International Journal of Obesity·2011· 32 citedOpen Access

Frequent Co-authors

Lora K. Heisler(12), Giuseppe D’Agostino(6), Alastair S. Garfield(6), Mark L. Evans(5), D. Lyons(4), Claudia Cristiano(4), Martin G. Myers(4), Barbora Doslikova(4), Teodora Georgescu(4), Justin J. Rochford(4), Joseph C. Madara(3), Ana Paula García(3), Bradford B. Lowell(3), Pablo B. Martínez de Morentin(3), Marcelo Rubinstein(3), Malcolm J. Low(3), Tamana Darwish(3), Althea R Cavanaugh(3), Sam Virtue(3), Emma Roth(3)