Paul Cheresh

Northwestern University — United States

Medicine · Health Sciences

28h-index3.1kcitations49works0.02yr avg
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Research Topics

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis(20), Occupational and environmental lung diseases(12), Parathyroid Disorders and Treatments(4), Autophagy in Disease and Therapy(4), Medical Imaging and Pathology Studies(4)

Publications49 total

Heavy-chain antibody targeting of CD38 NAD+ hydrolase ectoenzyme to prevent fibrosis in multiple organs
Scientific Reports·2023· 8 citedOpen Access
Long Noncoding RNA FENDRR Inhibits Lung Fibroblast Proliferation via a Reduction of β-Catenin
International Journal of Molecular Sciences·2021· 20 citedOpen Access
SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment
International Journal of Molecular Sciences·2021· 44 citedOpen Access
Magneto mitochondrial dysfunction mediated cancer cell death using intracellular magnetic nano-transducers
Biomaterials Science·2021· 17 citedOpen Access
Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis
iScience·2020· 59 citedOpen Access
Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function
Journal of Clinical Investigation·2020· 81 citedOpen Access
The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Pulmonary Fibrosis by Reducing Lung Epithelial Cell mtDNA Damage and Recruitment of Fibrogenic Monocytes
International Journal of Molecular Sciences·2020· 25 citedOpen Access
Epigenetic regulation of the Klotho / Miz 1 axis in cigarette‐smoke extract (CSE)‐induced alveolar epithelial cell (AEC) mtDNA damage and apoptosis
The FASEB Journal·2020
Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis
American Journal of Physiology-Lung Cellular and Molecular Physiology·2020· 41 citedOpen Access
Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts
International Journal of Molecular Sciences·2020· 120 citedOpen Access
Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function
2020· 13 citedOpen Access
Targeting CD38-Dependent NAD+ Metabolism to Mitigate Multiple Organ Fibrosis
SSRN Electronic Journal·2020· 3 citedOpen Access
A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages
European Respiratory Journal·2019· 318 citedOpen Access
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis
American Journal of Physiology-Lung Cellular and Molecular Physiology·2019· 38 citedOpen Access
The Sphingosine Kinase 1 Inhibitor, PF543, Mitigates Asbestos-Induced Pulmonary Fibrosis and Lung mtDNA Damage in Mice
2019· 1 cited
Epigenetic Regulation of the Klotho/miz1 Axis Promotes Cigarette-Smoke Extract (CSE)-Induced Alveolar Epithelial Cell (AEC) mtDNA Damage and Apoptosis
2019
700 Targeting SIRT/CD38/NAD+ homeostasis to mitigate fibrosis in scleroderma
Journal of Investigative Dermatology·2019Open Access
Single-cell RNA-seq reveals spatially restricted multicellular fibrotic niches during lung fibrosis
2019· 6 citedOpen Access
Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis
American Journal of Physiology-Lung Cellular and Molecular Physiology·2017· 44 citedOpen Access
SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis
The FASEB Journal·2017· 133 cited
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Frequent Co-authors

David W. Kamp(27), G. R. Scott Budinger(11), Karen M. Ridge(10), Seok-Jo Kim(9), Renea Jablonski(9), Anna P. Lam(8), Terrence A. Barrett(8), Anjana V. Yeldandi(7), Luisa Morales‐Nebreda(6), John Varga(6), Tatiana Goretsky(6), Satoshi Watanabe(5), Cara J. Gottardi(5), Alexander V. Misharin(5), Viswanathan Natarajan(5), Elizabeth Managlia(5), Nikita Joshi(4), Yuan Cheng(4), Mahzad Akbarpour(4), Jeffrey B. Brown(4)