Serena Barral

Great Ormond Street Hospital — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.4kcitations49works1.42yr avg
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Research Topics

Pluripotent Stem Cells Research(11), Genetics and Neurodevelopmental Disorders(8), CRISPR and Genetic Engineering(5), Neurogenesis and neuroplasticity mechanisms(4), Endoplasmic Reticulum Stress and Disease(4)

Publications49 total

An in vivo and in vitro spatiotemporal profile of human midbrain development
Nature Communications·2026Open Access
T42. INTEGRATING GENOMIC AND PHARMACOLOGICAL DATA FOR DRUG DISCOVERY IN MAJOR DEPRESSIVE DISORDER
European Neuropsychopharmacology·2025
An iPSC-derived neuronal model reveals manganese’s role in neuronal endocytosis, calcium flux and mitochondrial bioenergetics
iScience·2025· 1 citedOpen Access
Genetically informed drug target prioritisation and repurposing for major depressive disorder
2025Open Access
Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development
2025Open Access
Generation of an induced pluripotent stem cell line (UCLi026-A) from a patient with ADCY5-related disease carrying the heterozygous variant c.1253G > A; (p. Arg418Gln)
Stem Cell Research·2025Open Access
A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics
2024· 1 citedOpen Access
An in vivo and in vitro spatiotemporal atlas of human midbrain development
2024
Author response: Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2024Open Access
Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2024· 2 citedOpen Access
Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2024Open Access
Reviewer #2 (Public Review): Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2024Open Access
Reviewer #1 (Public Review): Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2024Open Access
Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2024Open Access
Neurodevelopmental and synaptic defects in <i>DNAJC6</i> parkinsonism, amenable to gene therapy
Brain·2024· 17 citedOpen Access
Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency
2023· 2 citedOpen Access
Dopamine Transporter Deficiency Syndrome (DTDS): Expanding the Clinical Phenotype and Precision Medicine Approaches
Cells·2023· 18 citedOpen Access
Gene Therapy for Dopamine Dyshomeostasis: From Parkinson's to Primary Neurotransmitter Diseases
Movement Disorders·2023· 21 citedOpen Access
Histone lysine methyltransferase-related neurodevelopmental disorders: current knowledge and saRNA future therapies
Frontiers in Cell and Developmental Biology·2023· 7 citedOpen Access
Automated high-content imaging in iPSC-derived neuronal progenitors
SLAS DISCOVERY·2023· 6 citedOpen Access
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Frequent Co-authors

Manju A. Kurian(25), Dimitri Budinger(13), Apostolos Papandreou(12), Paul Gissen(10), Katy Barwick(10), Joanne Ng(8), Lorita Gianfrancesco(8), Christin Luft(8), János Kriston-Vizi(8), Robin Ketteler(8), Jurjen W. Westra(7), Jerold Chun(7), Nivedita Singh(7), Alexander Agrotis(7), An‐Sofie Lenaerts(7), Allison Gregory(7), Suh Young Jeong(7), Penelope Hogarth(7), Susan J. Hayflick(7), Simon Pope(6)