Jason Carnes

Medicine · Health Sciences

19h-index1.4kcitations47works1.52yr avg
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Research Topics

Trypanosoma species research and implications(30), CRISPR and Genetic Engineering(12), Viral Infections and Immunology Research(11), Malaria Research and Control(10), RNA and protein synthesis mechanisms(10)

Publications47 total

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists.
PubMed·2026Open Access
Deep mutational scanning of the RNase III-like domain in Trypanosoma brucei RNA editing protein KREPB4
Frontiers in Cellular and Infection Microbiology·2024· 3 citedOpen Access
RNA editing catalytic complexes edit multiple mRNA sites non-processively in Trypanosoma brucei
Molecular and Biochemical Parasitology·2023· 2 citedOpen Access
Multiple domains of the integral KREPA3 protein are critical for the structure and precise functions of RNA editing catalytic complexes in <i>Trypanosoma brucei</i>
RNA·2023· 3 citedOpen Access
Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge
PLoS Pathogens·2023· 11 citedOpen Access
Multiple domains of the integral KREPA3 protein are critical for the structure and precise functions of RNA Editing Catalytic Complexes in <i>Trypanosoma brucei</i>
2023Open Access
Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection
Frontiers in Immunology·2022· 9 citedOpen Access
Distinct immune responses associated with vaccination status and protection outcomes after malaria challenge
2022Open Access
KRGG1 function in RNA editing in<i>Trypanosoma brucei</i>
RNA·2022· 7 citedOpen Access
Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection
2022· 3 citedOpen Access
Domain function and predicted structure of three heterodimeric endonuclease subunits of RNA editing catalytic complexes in <i>Trypanosoma brucei</i>
Nucleic Acids Research·2022· 6 citedOpen Access
Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity
PLoS Pathogens·2022· 10 citedOpen Access
Author response: Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case–control study
2021Open Access
Systems analysis of immune responses to attenuated <i>P. falciparum</i> malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity
2021Open Access
Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers
Malaria Journal·2021· 9 citedOpen Access
A baseline transcriptional signature associates with clinical malaria risk in RTS,S/AS01-vaccinated African children
2021· 1 citedOpen Access
Additional file 1 of Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers
Figshare·2021Open Access
Random mutagenesis identifies a novel essential domain in editosome RNase III proteins that are required for editing and differ between life cycle stages in Trypanosoma brucei
2020
Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes
Trends in Parasitology·2020· 109 citedOpen Access
Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in <i>Trypanosoma brucei</i>
RNA·2019· 13 citedOpen Access
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Frequent Co-authors

Kenneth Stuart(29), Suzanne M. McDermott(22), Ken Stuart(11), Fergal J. Duffy(8), Ying Du(8), M. Juliana McElrath(8), Nancy Lewis Ernst(6), Maxwell L. Neal(6), Katharine V. Schwedhelm(6), Nina Hertoghs(6), Maxmillian Mpina(5), Claudia Daubenberger(5), Stephen C. De Rosa(5), Atashi Anupama(4), Achim Schnaufer(4), Xuemin Guo(4), Damian A. Oyong(4), John D. Aitchison(4), Evan W. Newell(4), John D. Aitchison(4)