Alejandra Trejo‐Martin

BioClinica (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index744citations22works13.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Carcinogens and Genotoxicity Assessment(10), Computational Drug Discovery Methods(7), Chemical Synthesis and Analysis(3), Pesticide and Herbicide Environmental Studies(3), Sulfur Compounds in Biology(3)

Publications22 total

Impurity Qualification Thresholds: An IQ Survey on Emerging Industry Experience with Health Authority Feedback
Organic Process Research & Development·2025
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions
Regulatory Toxicology and Pharmacology·2025· 6 citedOpen Access
N-Nitrosamine drug substance related impurities (NDSRIs) – A proposal for the addition of subcategories to carcinogenic potency categorization approach categories 1 and 2 for NDSRIs with a molecular weight > 200 Da
Regulatory Toxicology and Pharmacology·2024· 11 cited
Quantum-Mechanics Calculations Elucidate Skin-Sensitizing Pharmaceutical Compounds
Chemical Research in Toxicology·2024· 5 cited
Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency
Chemical Research in Toxicology·2024· 43 cited
Acceptable intakes (AIs) for 11 small molecule N-nitrosamines (NAs)
Regulatory Toxicology and Pharmacology·2023· 29 citedOpen Access
Invited Editorial: Occupational Toxicology Testing Results for 25 Peptide Couplers
The Journal of Organic Chemistry·2022
Use of the bacterial reverse mutation assay to predict carcinogenicity of N-nitrosamines
Regulatory Toxicology and Pharmacology·2022· 40 citedOpen Access
The utility of hERG channel inhibition data in the derivation of occupational exposure limits
Regulatory Toxicology and Pharmacology·2022· 2 cited
An Evaluation of the Occupational Health Hazards of Peptide Couplers
Chemical Research in Toxicology·2022· 53 citedOpen Access
Corrigendum to a cross-industry collaboration to assess if acute toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling. Regulatory toxicology and pharmacology (2021) 104843
Regulatory Toxicology and Pharmacology·2022Open Access
In silico approaches in carcinogenicity hazard assessment: Current status and future needs
Computational Toxicology·2021· 40 citedOpen Access
Calculating qualified non-mutagenic impurity levels: Harmonization of approaches
Regulatory Toxicology and Pharmacology·2021· 12 cited
A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling
Regulatory Toxicology and Pharmacology·2020· 26 citedOpen Access
<i>In Vivo</i> Mutagenicity Testing of Arylboronic Acids and Esters
Environmental and Molecular Mutagenesis·2019· 14 cited
Genetic toxicology in silico protocol
Regulatory Toxicology and Pharmacology·2019· 78 citedOpen Access
Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi® and Epclusa®
Bioorganic & Medicinal Chemistry Letters·2019· 31 citedOpen Access
Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses
Regulatory Toxicology and Pharmacology·2018· 31 citedOpen Access
Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: is aromatic<i>N</i>-oxide a structural alert for predicting DNA-reactive mutagenicity?*
Mutagenesis·2018· 17 citedOpen Access
In silico toxicology protocols
Regulatory Toxicology and Pharmacology·2018· 234 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Joel P. Bercu(16), Robert A. Jolly(8), Michelle Kenyon(8), Glenn J. Myatt(7), Kevin P. Cross(7), James Harvey(7), Laura Custer(6), Krista L. Dobo(6), Susanne Glowienke(6), Angela White(6), Catrin Hasselgren(6), Jessica Graham(6), Alexander Amberg(5), Lennart T. Anger(5), Phillip Bellion(5), Naomi L. Kruhlak(5), Penny Leavitt(5), John Nicolette(5), Melisa Masuda-Herrera(5), Alessandro Brigo(4)