Nelson Rhodes

Chemistry · Physical Sciences

14h-index2.4kcitations33works0.02yr avg
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Research Topics

Synthesis and biological activity(8), Synthesis of Tetrazole Derivatives(8), PI3K/AKT/mTOR signaling in cancer(5), Fungal and yeast genetics research(4), Cancer-related Molecular Pathways(4)

Publications33 total

Supplementary Figure 2 from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Supplementary Figure 2 from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Supplementary Methods and Figure Legends 1-2 from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Data from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Supplementary Methods and Figure Legends 1-2 from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Data from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Supplementary Figure 1 from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
Supplementary Figure 1 from Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
2023Open Access
STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast.
UNC Libraries·2021Open Access
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.
UNC Libraries·2021Open Access
KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism
PLoS ONE·2015· 18 citedOpen Access
Inflammation and Resolution Are Associated with Upregulation of Fatty Acid β-Oxidation in Zymosan-Induced Peritonitis
PLoS ONE·2013· 36 citedOpen Access
Metabolic Perturbance in Autism Spectrum Disorders: A Metabolomics Study
Journal of Proteome Research·2012· 237 cited
2,3,5-Trisubstituted pyridines as selective AKT inhibitors—Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity
Bioorganic & Medicinal Chemistry Letters·2009· 15 citedOpen Access
2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles
Bioorganic & Medicinal Chemistry Letters·2009· 12 citedOpen Access
Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3<i>S</i>)-3-piperidinylmethyl]oxy}-1<i>H</i>-imidazo[4,5-<i>c</i>]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase
Journal of Medicinal Chemistry·2008· 155 citedOpen Access
Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
Cancer Research·2008· 296 citedOpen Access
Identification of a novel inhibitor of AKT kinase, GSK690693.
2007
Chemotherapy-induced alopecia: psychosocial impact and therapeutic approaches
Supportive Care in Cancer·2004· 159 cited
A simple method for predicting serum protein binding of compounds from IC 50 shift analysis for in vitro assays
Bioorganic & Medicinal Chemistry Letters·2004· 17 cited
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Frequent Co-authors

Tona M. Gilmer(15), Timothy J. Lansing(14), Zhihong Lai(14), Edgar R. Wood(13), Dirk A. Heerding(13), Anthony E. Choudhry(13), Elisabeth A. Minthorn(13), Victoria B. Knick(12), Derek R. Duckett(11), Derek J. Eberwein(11), Kimberly A. Robell(11), Jack D. Leber(11), Susan L. Strum(11), Robert A. Copeland(11), Randy T. McConnell(10), Jason A. Kahana(10), Robert S. Geske(10), Elena Kleymenova(10), Pearl S. Huang(10), Shuyun Zhang(8)