Bernard L. Silverman

Office of Chief Medical Examiner — United States

Medicine · Health Sciences

41h-index8.8kcitations128works3.52yr avg
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Research Topics

Opioid Use Disorder Treatment(24), Schizophrenia research and treatment(23), Substance Abuse Treatment and Outcomes(21), Treatment of Major Depression(17), Growth Hormone and Insulin-like Growth Factors(13)

Publications128 total

New Reduced Drinking Goals in Alcohol Pharmacotherapy Trials—A Novel Public-Private Effort and FDA Approval Process
JAMA Psychiatry·2025· 1 cited
Reductions in World Health Organization Risk Drinking Levels as a Primary Efficacy End Point for Alcohol Clinical Trials
JAMA Psychiatry·2025· 6 citedOpen Access
Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers
Neuropsychopharmacology·2021· 13 citedOpen Access
An Evidence-Based Review of OLZ/SAM for Treatment of Adults with Schizophrenia or Bipolar I Disorder [Corrigendum]
Neuropsychiatric Disease and Treatment·2021Open Access
An Evidence-Based Review of OLZ/SAM for Treatment of Adults with Schizophrenia or Bipolar I Disorder
Neuropsychiatric Disease and Treatment·2021· 21 citedOpen Access
A phase 3, multicenter study to assess the 1-year safety and tolerability of a combination of olanzapine and samidorphan in patients with schizophrenia: Results from the ENLIGHTEN-2 long-term extension
Schizophrenia Research·2021· 39 citedOpen Access
Phase 3 Safety and Tolerability Results of the Combination Olanzapine and Samidorphan in Patients with Schizophrenia: The 1 Year ENLIGHTEN-2-Extension
CNS Spectrums·2021· 2 citedOpen Access
A Combination of Olanzapine and Samidorphan in Adults with Schizophrenia and Bipolar I Disorder: Overview of Clinical Data
CNS Spectrums·2021· 2 citedOpen Access
Ultra long‐acting oral therapies for Alzheimer's: Proof of principle
Alzheimer s & Dementia·2020· 2 citedOpen Access
Effects of Olanzapine Combined With Samidorphan on Weight Gain in Schizophrenia: A 24-Week Phase 3 Study
American Journal of Psychiatry·2020· 118 cited
Reply to Kunoe (2020) and Ghosh &amp; Singh (2020) regarding Nunes <i>et al</i>. (2020): Opioid use and dropout from extended‐release naltrexone in a controlled trial: implications for mechanism
Addiction·2020· 1 citedOpen Access
Transition of Patients with Opioid Use Disorder from Buprenorphine to Extended‐Release Naltrexone: A Randomized Clinical Trial Assessing Two Transition Regimens
American Journal on Addictions·2020· 11 citedOpen Access
100 Olanzapine/Samidorphan for Schizophrenia: Weight Gain and Metabolic Outcomes in Phase 3 ENLIGHTEN-2 and Subsequent Long-Term, Open-Label Safety Study
CNS Spectrums·2020· 1 citedOpen Access
184 Insulin Sensitivity and Glucose Metabolism of Olanzapine and Combination Olanzapine and Samidorphan: A Phase 1 Exploratory Study in Healthy Volunteers
CNS Spectrums·2020· 2 citedOpen Access
Olanzapine Plus Samidorphan (ALKS 3831) in Schizophrenia and Comorbid Alcohol Use Disorder
The Journal of Clinical Psychiatry·2020· 19 cited
Efficacy and Safety of a Combination of Olanzapine and Samidorphan in Adult Patients With an Acute Exacerbation of Schizophrenia
The Journal of Clinical Psychiatry·2020· 54 citedOpen Access
P.758 Insulin sensitivity and glucose metabolism of olanzapine and a combination of olanzapine and samidorphan: phase 1 study in healthy volunteers
European Neuropsychopharmacology·2019
Opioid use and dropout from extended‐release naltrexone in a controlled trial: implications for mechanism
Addiction·2019· 21 citedOpen Access
Mitigation of Olanzapine-Induced Weight Gain With Samidorphan, an Opioid Antagonist: A Randomized Double-Blind Phase 2 Study in Patients With Schizophrenia
American Journal of Psychiatry·2019· 85 citedOpen Access
26 A Phase 3 Study to Determine the Antipsychotic Efficacy and Safety of ALKS 3831 in Adult Patients with Acute Exacerbation of Schizophrenia
CNS Spectrums·2019· 5 citedOpen Access
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Frequent Co-authors

Elliot Ehrich(10), Boyd E. Metzger(8), Aslı Memişoğlu(7), Lauren DiPetrillo(7), David R. Gastfriend(4), Thomas A. Rizzo(4), Yangchun Du(4), Ying Jiang(4), Evgeny Krupitsky(3), Edward V. Nunes(3), Walter Ling(3), Nam H. Cho(3), Edward S. Ogata(3), Reema L. Habiby(3), Ryan Z. Turncliff(3), Christoph U. Correll(3), Christine Graham(3), Adam Simmons(3), David McDonnell(3), Jacqueline Zummo(3)