Mei‐Chin Lu

National Museum of Marine Biology and Aquarium — Taiwan

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index2.7kcitations120works0.82yr avg
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Research Topics

Marine Sponges and Natural Products(66), Microbial Natural Products and Biosynthesis(43), Synthetic Organic Chemistry Methods(27), Bioactive Compounds and Antitumor Agents(16), Synthesis and Biological Activity(12)

Publications120 total

A New Secondary Metabolite with Cytotoxicity from Formosa Tithonia diversifolia
Chemistry of Natural Compounds·2025
Heteronemin suppresses EGF‑induced proliferation through the PI3K/PD‑L1 signaling pathways in cholangiocarcinoma
Oncology Reports·2025· 1 cited
From Sea to Science: Coral Aquaculture for Sustainable Anticancer Drug Development
Marine Drugs·2024· 1 citedOpen Access
Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells
Journal of Dental Sciences·2024· 1 citedOpen Access
Heteronemin promotes iron-dependent cell death in pancreatic cancer
Naunyn-Schmiedeberg s Archives of Pharmacology·2023· 8 cited
Screening of marine Actinomycetia with bioactive metabolites from nearshore and deep sea marine sediments in southwestern Taiwan
Biologia·2023· 1 cited
Exploration of anti‐leukemic effect of soft coral‐derived 13‐acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase <scp>II</scp>
The Kaohsiung Journal of Medical Sciences·2023· 2 citedOpen Access
13-Epi-9-Deacetylxenicin Derivatives from a Taiwanese Soft Coral Asterospicularia laurae and Treir Cytotoxic Activity
Chemistry of Natural Compounds·2022· 1 cited
The Antileukemic and Anti-Prostatic Effect of Aeroplysinin-1 Is Mediated through ROS-Induced Apoptosis via NOX Activation and Inhibition of HIF-1a Activity
Life·2022· 17 citedOpen Access
Heteronemin Promotes Iron-Dependent Cell Death in Pancreatic Cancer
Research Square (Research Square)·2022· 1 citedOpen Access
The Anti-Proliferative Activity of Secondary Metabolite from the Marine Streptomyces sp. against Prostate Cancer Cells
Life·2021· 20 citedOpen Access
The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90
Molecules·2021· 8 citedOpen Access
Effect of Estrogen on Heteronemin-Induced Anti-proliferative Effect in Breast Cancer Cells With Different Estrogen Receptor Status
Frontiers in Cell and Developmental Biology·2021· 14 citedOpen Access
The Configuration-Dependent Anti-Leukemic Effect of Manoalide Stereoisomers: Reignite Research Interest in these Sponge-Derived Sesterterpenoids
Bioorganic Chemistry·2021· 10 cited
A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways
Oxidative Medicine and Cellular Longevity·2021· 127 citedOpen Access
13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity against Oral Cancer Cells through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts
Marine Drugs·2020· 29 citedOpen Access
Probing Anti-Proliferative 24-Homoscalaranes from a Sponge Lendenfeldia sp.
Marine Drugs·2020· 12 citedOpen Access
New secondary metabolite with cytotoxicity from spawning soft coral <i>Asterospicularia laurae</i> in Taiwan
Natural Product Research·2019· 10 cited
The Antioxidant from Ethanolic Extract of Rosa cymosa Fruits Activates Phosphatase and Tensin Homolog In Vitro and In Vivo: A New Insight on Its Antileukemic Effect
International Journal of Molecular Sciences·2019· 25 citedOpen Access
Antimicrobial activity and diversity of bacteria associated with Taiwanese marine sponge Theonella swinhoei
Annals of Microbiology·2019· 35 citedOpen Access
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Frequent Co-authors

Yang‐Chang Wu(23), Mohamed El‐Shazly(16), Ping‐Jyun Sung(16), Fang‐Rong Chang(11), Ying-Chi Du(8), Jui‐Hsin Su(8), Jui-Hsin Su(8), Yu‐Ming Hsu(7), Kuei-Hung Lai(7), Ying-Chi Du(7), Yi‐Chang Liu(6), Shou‐Ping Shih(6), Ching‐Feng Weng(5), Juan-Cheng Yang(5), Zhi‐Hong Wen(5), Tsong‐Long Hwang(5), Yu‐Cheng Chen(5), Lee-Shing Fang(5), Tung-Ying Wu(4), Yu‐Chia Chang(4)