Laurent Kreplak

Dalhousie University — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

37h-index5.0kcitations141works1.02yr avg
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Research Topics

Cellular Mechanics and Interactions(43), Collagen: Extraction and Characterization(39), Skin and Cellular Biology Research(33), Silk-based biomaterials and applications(21), Tendon Structure and Treatment(15)

Publications141 total

In tendons, differing physiological requirements lead to distinct patterns of MMP-1 degradation
Scientific Reports·2025Open Access
Second harmonic generation of myofibrils exhibits a polarization-resolved “gradient” effect
Biomedical Optics Express·2025Open Access
Polarization-Resolved Second Harmonic Generation Microscopy of Silk Fibers Is Sensitive to β-Sheet Orientation and Molecular Structure
ACS Applied Bio Materials·2025· 1 cited
Polarization-resolved Second Harmonic Generation Microscopy for Investigating Muscle and Collagen Fibrils
2025
Anisotropic swelling due to hydration constrains anisotropic elasticity in biomaterial fibers
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials·2024· 1 citedOpen Access
Formation of linear arrays of holes in self-assembled collagen films
Frontiers in Soft Matter·2024Open Access
Histological staining alters circular dichroism SHG measurements of collagen
Optics Letters·2024· 6 cited
Determining the helical pitch and relative polarity of collagen using polarization-resolved SHG
2024· 1 cited
An interferometric-based tensile tester to resolve damage events within reconstituted multi-filaments collagen bundles
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials·2024Open Access
Anisotropic swelling due to hydration constrains anisotropic elasticity in biomaterial fibers
arXiv (Cornell University)·2023Open Access
Effect of out of plane orientation on polarization second harmonic generation of single collagen fibrils
Biomedical Optics Express·2023· 7 citedOpen Access
Individual Collagen Fibrils Investigated using Polarization-Resolved Second Harmonic Generation Microscopy
2023
Multifilament Collagen Fiber Bundles with Tendon‐like Structure and Mechanical Performance
Macromolecular Rapid Communications·2023· 2 citedOpen Access
Torsion and Bistability of Double-Twist Elastomers
arXiv (Cornell University)·2023Open Access
High numerical aperture imaging allows chirality measurement in individual collagen fibrils using polarization second harmonic generation microscopy
Nanophotonics·2023· 24 citedOpen Access
Single collagen fibrils isolated from high stress and low stress tendons show differing susceptibility to enzymatic degradation by the interstitial collagenase matrix metalloproteinase-1 (MMP-1)
Matrix Biology Plus·2023· 6 citedOpen Access
Torsion and bistability of double-twist elastomers
Soft Matter·2023
Characterizing Hydration and Buckling in Individual Collagen Fibrils with Polarization Second Harmonic Generation Microscopy
2023
Nonwoven Hemostatic Dressings Formed by Contact Drawing of Interposed Polyethylene Oxide (PEO)‐Fibrinogen and PEO‐Thrombin Microfibers
Advanced Materials Interfaces·2022· 11 citedOpen Access
Multi-pin contact drawing enables production of anisotropic collagen fiber substrates for alignment of fibroblasts and monocytes
Colloids and Surfaces B Biointerfaces·2022· 9 cited
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Frequent Co-authors

Ueli Aebi(13), Harald Herrmann(10), J. Doucet(6), Fatma Briki(6), H.A. Tajmir‐Riahi(6), Norbert Mücke(5), Harald Bär(4), E. Froehlich(4), J. S. Mandeville(4), Sergei V. Strelkov(3), Tatjana Wedig(3), Zhao Qin(3), Markus J. Buehler(3), C. M. Weinert(3), Douglas S. Fudge(3), Dmitri I. Svergun(3), P. Dumas(2), J.F. Leterrier(2), Robert Kirmse(2), R. Marty(2)