Craig D. Dickinson

Eli Lilly (United States) — United States

Medicine · Health Sciences

31h-index2.9kcitations49works0.02yr avg
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Research Topics

Blood Coagulation and Thrombosis Mechanisms(11), Legume Nitrogen Fixing Symbiosis(11), Hemophilia Treatment and Research(10), Monoclonal and Polyclonal Antibodies Research(9), Coagulation, Bradykinin, Polyphosphates, and Angioedema(8)

Publications49 total

Preclinical Characterization of LY3209590, a Novel Weekly Basal Insulin Fc-Fusion Protein
Journal of Pharmacology and Experimental Therapeutics·2022· 51 citedOpen Access
Preclinical Characterization of Once Weekly Basal Insulin Fc (BIF)
Journal of the Endocrine Society·2021· 7 citedOpen Access
Utilizing Natural Frequency Monitoring and Machine Learning to Monitor and Predict Structural Integrity and Minimize the Cost of Fixed Offshore Platform Intervention
2020· 1 cited
LY-CoV555 neutralizing antibody against SARS-CoV-2
2020· 1 cited
Facile Preparation of Stable Antibody–Gold Conjugates and Application to Affinity-Capture Self-Interaction Nanoparticle Spectroscopy
Bioconjugate Chemistry·2016· 35 cited
Discovery of highly soluble antibodies prior to purification using affinity-capture self-interaction nanoparticle spectroscopy
Protein Engineering Design and Selection·2015· 44 citedOpen Access
Emerging methods for identifying monoclonal antibodies with low propensity to self-associate during the early discovery process
Expert Opinion on Drug Delivery·2014· 23 cited
Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates
Molecular Pharmaceutics·2013· 66 cited
FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
Drug Metabolism and Disposition·2012· 56 cited
Different roles of N‐ and C‐ termini in the functional activity of FGF21
Journal of Cellular Physiology·2008· 143 cited
A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen
Molecular Cancer Therapeutics·2004· 3 citedOpen Access
Optimization of protein therapeutics by directed evolution
Drug Discovery Today·2003· 61 cited
Prostate-specific membrane antigen directed selective thrombotic infarction of tumors.
PubMed·2002· 79 cited
Exosite Interactions Determine the Affinity of Factor X for the Extrinsic Xase Complex
Journal of Biological Chemistry·2000· 83 citedOpen Access
Macromolecular Substrate Affinity for the Tissue Factor-Factor VIIa Complex Is Independent of Scissile Bond Docking
Journal of Biological Chemistry·1999· 41 citedOpen Access
Regulation of the Catalytic Function of Coagulation Factor VIIa by a Conformational Linkage of Surface Residue Glu 154 to the Active Site
Biochemistry·1999· 25 cited
Importance of Factor VIIa Gla-Domain Residue Arg-36 for Recognition of the Macromolecular Substrate Factor X Gla-Domain
Biochemistry·1999· 40 cited
Allosteric Regulation of the Cofactor-Dependent Serine Protease Coagulation Factor VIIa
Trends in Cardiovascular Medicine·1998· 47 cited
Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor VIIa
Journal of Molecular Biology·1998· 48 cited
Active Site Modification of Factor VIIa Affects Interactions of the Protease Domain with Tissue Factor
Journal of Biological Chemistry·1997· 63 citedOpen Access
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Frequent Co-authors

Niels Chr. Nielsen(12), Wolfram Ruf(11), Thomas S. Edgington(5), Justin Shobe(5), Kathryn R. Ely(4), Maarten J. Chrispeels(4), Peter M. Tessier(4), Bernard J. Scallon(3), Ebtissam H. A. Hussein(3), Liliane A. Dickinson(3), Brian W. Tague(3), Jiemin Wu(3), Tae‐Ju Cho(2), Vu Huu Thanh(2), Thomas L. Sims(2), Robert B. Goldberg(2), B. Veerapandian(2), Xiaoping Dai(2), R. Hamlin(2), Erkki Ruoslahti(2)