David F. Ackerley

University of Auckland — New Zealand

Medicine · Health Sciences

38h-index4.3kcitations152works0.82yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(29), Cancer Research and Treatments(29), CRISPR and Genetic Engineering(19), Virus-based gene therapy research(15), Advanced biosensing and bioanalysis techniques(14)

Publications152 total

A minireview on oxygen-insensitive nitroreductases : reaction mechanisms and their biomedical impact
Chemija·2025Open Access
Novel TdsD nitroreductase: characterization of kinetics and substrate specificity
Biotechnology Letters·2025· 1 cited
A rapid combinatorial assembly method for gene cluster characterisation illuminates glidobactin biosynthesis
Synthetic and Systems Biotechnology·2025Open Access
Optimized chemogenetic ablation and regeneration of enteric nervous system neurons in zebrafish
2025Open Access
Purpuramine R, a New Bromotyrosine Isolated from Pseudoceratina cf. verrucosa Collected in the Kingdom of Tonga
Marine Drugs·2025· 1 citedOpen Access
Heterologous Expression of Epoxomicin in <i>Escherichia coli</i>
ACS Synthetic Biology·2024
A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regeneration
Development·2024· 4 citedOpen Access
Structural Evaluation of a Nitroreductase Engineered for Improved Activation of the 5-Nitroimidazole PET Probe SN33623
International Journal of Molecular Sciences·2024Open Access
The Catalysis Mechanism of E. coli Nitroreductase A, a Candidate for Gene-Directed Prodrug Therapy: Potentiometric and Substrate Specificity Studies
International Journal of Molecular Sciences·2024· 3 citedOpen Access
Molecular approaches for hexavalent chromium bioremediation: Stanford Medical Center
New Zealand Science Review·2024Open Access
Review for "Biochemical, kinetic, and structural characterization of a &lt;i&gt;Bacillus tequilensis&lt;/i&gt; nitroreductase"
2024
Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides
Nature Chemical Biology·2023· 21 cited
Molecular regulation of retinal regeneration is context specific
2023· 3 citedOpen Access
Preparation, analysis and toxicity characterisation of the redox metabolites of the azo food dye tartrazine
Food and Chemical Toxicology·2023· 21 citedOpen Access
Bioprospecting the unknown: how bacterial enzymes encoded by unknown genes might help clean up pollution
2023Open Access
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening
Cell chemical biology·2023· 4 citedOpen Access
mRNA vaccine against malaria tailored for liver-resident memory T cells
Nature Immunology·2023· 63 cited
An inducible model of chronic hyperglycemia
Disease Models & Mechanisms·2023· 5 citedOpen Access
Metagenomic domain substitution for the high-throughput modification of non-ribosomal peptide analogues
2023Open Access
Metagenomic domain substitution for the high-throughput modification of non-ribosomal peptide analogues
2023· 1 citedOpen Access
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Frequent Co-authors

Janine N. Copp(13), Adam V. Patterson(11), Jeremy G. Owen(10), Elsie M. Williams(10), Jeff B. Smaill(10), A. Matin(8), Mark J. Calcott(8), Alexandra M. Mowday(7), Alistair S. Brown(6), Christopher P. Guise(6), Robert A. Keyzers(5), Yoram Barak(4), Susan V. Lynch(4), Katherine Robins(4), Iain L. Lamont(4), Amir Ashoorzadeh(4), Abigail V. Sharrock(4), C. F. Gonzalez(3), M. Keyhan(3), Michelle H. Rich(3)