Alfonso García de Coca

Hospital Clínico Universitario de Valladolid — Spain

Medicine · Health Sciences

26h-index3.5kcitations109works0.72yr avg
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Research Topics

Chronic Lymphocytic Leukemia Research(36), Multiple Myeloma Research and Treatments(30), Lymphoma Diagnosis and Treatment(20), Amyloidosis: Diagnosis, Treatment, Outcomes(18), Acute Myeloid Leukemia Research(14)

Publications109 total

Measurable residual disease assessment in apheresis product from multiple myeloma patients: association with biology, depth of response and survival.
2026Open Access
Clinic-Biological Features and Prognostic Significance of MGUS-Like Myeloma who underwent to Autologous Stem Cell Transplantation
Clinical Lymphoma Myeloma & Leukemia·2025Open Access
ZMYM3 mutations modulate histone acetylation and cooperate with NOTCH1 mutations in chronic lymphocytic leukemia
2025Open Access
SAMHD1 dysfunction impairs DNA damage response and increases sensitivity to PARP inhibition in chronic lymphocytic leukemia
Scientific Reports·2025· 2 citedOpen Access
Preferential Genetic Pathways Lead to Relapses in Adult B-Cell Acute Lymphoblastic Leukemia
Cancers·2024· 2 citedOpen Access
Determining Outcome in IgM Gammopathies: Integration of Molecular, Flow Cytometry and Clinical Factors in an International, Multicenter Series (the SAL-TO Study)
Blood·2024
Mutually-Exclusive Pathways between <i>IKZF1</i> <i>plus</i> and RAS Mutations and <i>TP53</i> double-Hit Alterations Lead Relapse in B-Other, Ph-like and Hyperdiploidy Genetic Groups in Adult B-Cell Acute Lymphoblastic Leukemia
Blood·2023Open Access
<i>ZMYM3</i> Mutations Cooperate with <i>NOTCH1</i> Alterations, Reduce Histone H4 Acetylation and Promote Apoptosis Evasion in Chronic Lymphocytic Leukemia
Blood·2023· 2 cited
POSTER: AML-391 WHO and ICC 2022 Cytogenetic Abnormalities Defining Acute Myelogenous Leukemia (AML) Myelodysplasia-Related in First-Line Decitabine in Unfit AML Patients
Clinical Lymphoma Myeloma & Leukemia·2023
AML-391 WHO and ICC 2022 Cytogenetic Abnormalities Defining Acute Myelogenous Leukemia (AML) Myelodysplasia-Related in First-Line Decitabine in Unfit AML Patients
Clinical Lymphoma Myeloma & Leukemia·2023
P343: MUTATIONS IN GENES RELATED TO EPIGENETIC REGULATION, TREATMENT RESISTANCE AND IKZF1 PLUS PROFILE IDENTIFY RELAPSE PROFILES IN B-ALL.
HemaSphere·2023Open Access
PB2102: IMPACT OF AUTOLOGOUS STEM CELL TRASPLANTATION IN AL AMYLOIDOSIS. EXPERIENCE IN A SINGLE TERTIARY HOSPITAL
HemaSphere·2023Open Access
Novel Agents as Main Drivers for Continued Improvement in Survival in Multiple Myeloma
Cancers·2023· 67 citedOpen Access
Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma Included in the Compassionate Use or the Expanded Access Program. Experience with a Spanish Cohort
Blood·2022· 8 cited
P622: DOUBLE-HIT TRAF3 DELETION AND MUTATION IDENTIFIED BY HIGH-THROUGHPUT SEQUENCING DEFINE A NEW INDEPENDENT PROGNOSTIC FACTOR IN CHRONIC LYMPHOCYTIC LEUKEMIA
HemaSphere·2022Open Access
Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development
Blood·2021· 25 citedOpen Access
Pomalidomide, Cyclophosphamide, and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma: Real-World Analysis of the Pethema-GEM Experience
Clinical Lymphoma Myeloma & Leukemia·2021· 10 cited
Dissecting the role of <i>TP53</i> alterations in del(11q) chronic lymphocytic leukemia
Clinical and Translational Medicine·2021· 13 citedOpen Access
Clinical and Biological Impact of <i>TP53</i> Alterations in Del(11q) Chronic Lymphocytic Leukemia
Blood·2020· 1 cited
Comprehensive Custom NGS Panel Validation for the Improvement of the Stratification of B-Acute Lymphoblastic Leukemia Patients
Journal of Personalized Medicine·2020· 9 citedOpen Access
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Frequent Co-authors

Jesús F. San Miguel(24), Ramón García‐Sánz(19), María‐Victoria Mateos(18), José‐Ángel Hernández‐Rivas(18), María‐Belén Vídriales(16), Norma C. Gutiérrez(16), Marcos González(16), Bruno Paiva(14), Fernando Escalante(14), Enrique M. Ocio(14), Noemí Puig(14), Natalia de las Heras(13), María Eugenia Sarasquete(12), Jesús María Hernández‐Rivas(12), Abelardo Bárez(11), Rocí­o Benito(11), Josefina Galende(10), Alberto Órfão(10), Miguel Alcoceba(10), María Hernández‐Sánchez(10)