Ram Kannan

University of California, Los Angeles — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index5.5kcitations185works1.22yr avg
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Research Topics

Sulfur Compounds in Biology(38), Connexins and lens biology(36), Retinal Diseases and Treatments(35), Retinal Development and Disorders(18), Amino Acid Enzymes and Metabolism(16)

Publications184 total

Deficiency of 2‐Oxoglutarate Carrier (Slc25a11) Drives <scp>RPE</scp> Epithelial‐to‐Mesenchymal Transition and Exacerbates Subretinal Fibrosis in Neovascular Age‐Related Macular Degeneration
Aging Cell·2025Open Access
Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment
Investigative Ophthalmology & Visual Science·2025· 1 citedOpen Access
RAGE Is Essential for Subretinal Fibrosis in Laser-Induced Choroidal Neovascularization: Therapeutic Implications
Investigative Ophthalmology & Visual Science·2025· 3 citedOpen Access
Five-year Outcome of Aflibercept Administration with “Treat and Extend” for Neovascular Age-Related Macular Degeneration
Clinical ophthalmology·2025· 2 citedOpen Access
Study of Gonadal Hormones in NAFLD Patients
2025
αB-Crystallin Peptide Fused with Elastin-like Polypeptide: Intracellular Activity in Retinal Pigment Epithelial Cells Challenged with Oxidative Stress
Antioxidants·2023· 2 citedOpen Access
Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice
Antioxidants·2023· 7 citedOpen Access
Correction to: Persistence of vascular empty sleeves in choroidal neovascularization after anti-VEGF therapy in both animal models and humans
Graefe s Archive for Clinical and Experimental Ophthalmology·2023Open Access
Characterization and contribution of RPE senescence to Age-related macular degeneration in <i>Tnfrsf10</i> knock out mice
2023Open Access
Persistence of vascular empty sleeves in choroidal neovascularization after VEGF therapy in both animal models and humans
Graefe s Archive for Clinical and Experimental Ophthalmology·2023· 4 cited
Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr−/− Mice
Cells·2022· 25 citedOpen Access
Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide
Antioxidants·2022· 10 citedOpen Access
David Ralph Hinton, MD, FARVO – In Memoriam (1954–2022)
Experimental Eye Research·2022
<i>TNFRSF10A</i> downregulation induces retinal pigment epithelium degeneration during the pathogenesis of age-related macular degeneration and central serous chorioretinopathy
Human Molecular Genetics·2022· 11 citedOpen Access
Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD
Experimental Eye Research·2022· 38 citedOpen Access
Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration
Antioxidants·2021· 100 citedOpen Access
Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration
Redox Biology·2020· 28 citedOpen Access
Inhibition of mitochondrial GSH carrier proteins leading to mitochondrial dysfunction and restoration of function with αB crystallin peptide in human RPE cells
Investigative Ophthalmology & Visual Science·2020Open Access
Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells
Antioxidants·2020· 12 citedOpen Access
Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration
Progress in Retinal and Eye Research·2020· 464 citedOpen Access
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Frequent Co-authors

David R. Hinton(29), Parameswaran G. Sreekumar(21), Christine Spee(15), Stephen J. Ryan(11), Neil Kaplowitz(8), Ernesto Barrón(6), Keijiro Ishikawa(5), Shikun He(4), Jennifer Yaung(4), Berislav V. Zloković(4), Kai Kaarniranta(3), Szabolcs Felszeghy(3), Antero Salminen(3), Debasish Sinha(3), Deborah A. Ferrington(3), Shozo Sonoda(3), Murad Ookhtens(3), Eric F. Wawrousek(3), Diana Tang(3), Hiroto Terasaki(3)