Greg Poffenberger

Vanderbilt University Medical Center — United States

Medicine · Health Sciences

27h-index3.3kcitations56works2.52yr avg
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Research Topics

Pancreatic function and diabetes(47), Diabetes and associated disorders(25), Diabetes Management and Research(18), Diabetes Treatment and Management(10), Metabolism, Diabetes, and Cancer(10)

Publications55 total

Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods
2024· 4 citedOpen Access
Heterogeneous endocrine cell composition defines human islet functional phenotypes
2024· 3 citedOpen Access
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
Molecular Metabolism·2024· 3 citedOpen Access
Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners
2024Open Access
Genetic risk converges on regulatory networks mediating early type 2 diabetes
Nature·2023· 63 citedOpen Access
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2
2023· 10 citedOpen Access
Dataset from Shrestha et al., JCI Insight (2021)
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Dataset from Shrestha et al., JCI Insight (2021)
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes
2021· 9 citedOpen Access
Exploiting LY3009120 and Asciminib Combination to Target TKI-Resistant CML
Blood·2021· 3 cited
Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes
Journal of the Endocrine Society·2021· 2 citedOpen Access
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells
JCI Insight·2021· 42 citedOpen Access
Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration
npj Regenerative Medicine·2021· 33 citedOpen Access
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells
2021· 3 citedOpen Access
Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets
Proceedings of the National Academy of Sciences·2021· 45 citedOpen Access
Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration
2020Open Access
255-OR: ADA Presidents’ Select Abstract: Glucagon Receptor Antagonism Stimulates Beta-Cell Proliferation in Mouse and Human Islets
Diabetes·2020
1894-P: Interruption of Glucagon Signaling Increases Pancreas Mass
Diabetes·2020
Dapagliflozin Does Not Directly Affect Human α or β Cells
Endocrinology·2020· 15 citedOpen Access
Decreased pancreatic acinar cell number in type 1 diabetes
Diabetologia·2020· 67 citedOpen Access
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Frequent Co-authors

Alvin C. Powers(46), Marcela Briššová(24), Radhika Aramandla(21), Chunhua Dai(17), Nripesh Prasad(14), Rita Bottino(13), Alena Shostak(12), Diane C. Saunders(12), Shawn Levy(11), Dale L. Greiner(11), John T. Walker(11), Shristi Shrestha(10), E. Danielle Dean(9), Leonard D. Shultz(8), Roland Stein(7), Rachana Haliyur(7), Maureen Gannon(6), Kristie Aamodt(6), Nathaniel Hart(6), John Virostko(6)