Yu Nee Lee

Tel Aviv University — Israel

Immunology and Microbiology · Life Sciences

31h-index2.9kcitations65works5.02yr avg
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Research Topics

Immunodeficiency and Autoimmune Disorders(41), Immune Cell Function and Interaction(26), T-cell and B-cell Immunology(20), CAR-T cell therapy research(8), Blood disorders and treatments(8)

Publications65 total

Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells
Journal of Clinical Immunology·2025· 1 citedOpen Access
Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature
Science Immunology·2025· 9 citedOpen Access
Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK
Journal of Clinical Immunology·2023· 7 citedOpen Access
CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications
Nature Communications·2023· 20 citedOpen Access
CRISPR-Cas9 RAG2 Correction via Coding Sequence Replacement to Preserve Endogenous Gene Regulation and Locus Structure
2023· 1 citedOpen Access
Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs
Molecular Therapy — Nucleic Acids·2022· 36 citedOpen Access
SLP76 Mutation Associated with Combined Immunodeficiency and EBV-Related Lymphoma
Journal of Clinical Immunology·2022· 11 cited
Multiplex HDR for Disease and Correction Modeling of SCID by CRISPR Genome Editing in Human HSPCs
2022Open Access
Inadequate Activation of γδT- and B-cells in Patient with Wiskott-Aldrich Syndrome (WAS) Portrayed by TRG and IGH Repertoire Analyses
Journal of Clinical Immunology·2022Open Access
Novel NHEJ1 pathogenic variant linked to severe combined immunodeficiency, microcephaly, and abnormal T and B cell receptor repertoires
Frontiers in Pediatrics·2022· 5 citedOpen Access
Lessons Learned From Five Years of Newborn Screening for Severe Combined Immunodeficiency in Israel
The Journal of Allergy and Clinical Immunology In Practice·2022· 24 cited
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia
Nature Communications·2022· 31 citedOpen Access
B cell repertoire in patients with a novel BTK mutation: expanding the spectrum of atypical X-linked agammaglobulinemia
Immunologic Research·2022· 2 cited
Novel XLF/Cernunnos mutation linked to severe combined immunodeficiency, microcephaly and abnormal T and B cell receptor repertoires
2021
Exploring genetic defects in adults who were clinically diagnosed as severe combined immune deficiency during infancy
Immunologic Research·2021· 5 cited
Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects
The Journal of Experimental Medicine·2020· 31 citedOpen Access
Immune and TRG repertoire signature of the thymus in Down syndrome patients
Pediatric Research·2020· 4 cited
Alterations in T and B Cell Receptor Repertoires Patterns in Patients With IL10 Signaling Defects and History of Infantile-Onset IBD
Frontiers in Immunology·2020· 17 citedOpen Access
An instructive role for IL7RA in the development of human B-cell precursor leukemia
2020· 5 citedOpen Access
A Large Cohort of RAG1/2-Deficient SCID Patients—Clinical, Immunological, and Prognostic Analysis
Journal of Clinical Immunology·2019· 21 cited
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Frequent Co-authors

Luigi D. Notarangelo(27), Raz Somech(17), Jolán E. Walter(14), Atar Lev(13), Anthony Simon(11), Francesco Frugoni(10), Kerry Dobbs(9), Waleed Al–Herz(8), Irit Tirosh(7), Silvia Giliani(7), Karin Chen(6), Andrew R. Gennery(6), Tali Stauber(6), Ayal Hendel(6), Krisztián Csomós(5), Caterina Cancrini(5), Raif S. Geha(5), Ehud Razin(5), Lauren A. Henderson(5), Ortal Barel(5)