Alice Chen‐Plotkin

University of Pennsylvania — United States

Medicine · Health Sciences

65h-index20.7kcitations243works5.82yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(109), Alzheimer's disease research and treatments(93), Dementia and Cognitive Impairment Research(59), Amyotrophic Lateral Sclerosis Research(41), Neurological diseases and metabolism(34)

Publications242 total

Microglial reactivity in the hippocampal CA2 is associated with advanced neuronal α-synucleinopathy
2026Open Access
Secreted GPNMB enhances uptake of fibrillar alpha-synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies
2026Open Access
Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch
JAMA Neurology·2025Open Access
CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies
Neurology·2025· 2 cited
Mapping the developmental path for Parkinson’s disease therapeutics
npj Parkinson s Disease·2025Open Access
Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer’s Disease using PET and Plasma Biomarkers
2025Open Access
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of frontotemporal dementia
Molecular Neurodegeneration·2025· 2 citedOpen Access
Medial temporal lobe Tau-Neurodegeneration <i>mismatch</i> from MRI and plasma biomarkers identifies vulnerable and resilient phenotypes with AD
2025Open Access
Tau-Clinical Mismatch Identifies Individuals with Co-Pathology and Predicts Clinical Trajectory
2025Open Access
Tau burden is best captured by magnitude and extent: Tau‐MaX as a measure of global tau
Alzheimer s & Dementia·2025· 5 citedOpen Access
Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies
Annals of Neurology·2025· 3 citedOpen Access
Parkinson’s disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction
npj Parkinson s Disease·2025· 10 citedOpen Access
The Source and Pathogenic Potential of Blood-derived Alpha-Synuclein (S4.010)
Neurology·2025
Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes
Annals of Clinical and Translational Neurology·2025· 1 citedOpen Access
Tau Burden is Best Captured by Magnitude and Extent: Tau-MaX as a Measure of Global Tau
2025· 9 citedOpen Access
Tau Magnitude and eXent–Tau‐MaX: Capturing tau spread and local accumulation provides a robust metric of tau burden
Alzheimer s & Dementia·2024Open Access
Novel microglial markers that are specifically increased in early clinical AD stages
Alzheimer s & Dementia·2024Open Access
Comparison of plasma p‐tau<sub>217</sub> and Aβ<sub>42</sub>/Aβ<sub>40</sub> biomarkers by race to detect Alzheimer’s disease
Alzheimer s & Dementia·2024· 1 citedOpen Access
Improving detection of concomitant Alzheimer’s disease pathology in autopsied Lewy body disorders using CSF biomarkers
Alzheimer s & Dementia·2024Open Access
Combining plasma biomarkers for β‐amyloid diagnosis and cognitive prognosis across the clinical spectrum: normal, amnestic, and non‐amnestic
Alzheimer s & Dementia·2024Open Access
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Frequent Co-authors

John Q. Trojanowski(34), Virginia M.‐Y. Lee(25), Vivianna M. Van Deerlin(22), Daniel Weintraub(20), Murray Grossman(19), Leo McCluskey(14), Lauren Elman(13), David J. Irwin(11), James B. Leverenz(10), Sharon X. Xie(10), Howard I. Hurtig(10), Andrew Siderowf(10), Leslie M. Shaw(10), Thomas J. Montine(8), Jon B. Toledo(8), David A. Wolk(8), Douglas Galasko(7), Edward B. Lee(7), Steven E. Arnold(7), EunRan Suh(6)