Alejandro D. Montaner

Hospital César Milstein — Argentina

Medicine · Health Sciences

13h-index579citations45works1.32yr avg
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Research Topics

Pancreatic function and diabetes(8), Hypothalamic control of reproductive hormones(8), Pain Mechanisms and Treatments(7), Immune Response and Inflammation(7), Immunotherapy and Immune Responses(6)

Publications45 total

IMT504 accelerates post-hepatectomy liver regeneration in mice with involvement of GLAST + Wnt1 + bone marrow stromal progenitors
Scientific Reports·2025Open Access
The antifibrotic potential of IMT504: modulation of GLAST + Wnt1 + bone marrow stromal progenitors and hepatic microenvironment
Stem Cell Research & Therapy·2024· 2 citedOpen Access
Mesenchymal Stem Cell Engagement Modulates Neuroma Microenviroment in Rats and Humans and Prevents Postamputation Pain
Journal of Pain·2024· 2 citedOpen Access
SAT035 Oligonucleotide IMT504 Markedly Improves Metabolic Sindrome And Type 2 Diabetes In High-Fat Diet Fed Mice
Journal of the Endocrine Society·2023Open Access
IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation
Physiological Reports·2023· 2 citedOpen Access
Modulation of the Inflammatory Response by Pre-emptive Administration of IMT504 Reduces Postoperative Pain in Rats and has Opioid-Sparing Effects
Journal of Pain·2023· 6 citedOpen Access
Modulation of Mesenchymal Stem Cells, Glial Cells and the Immune System by Oligodeoxynucleotides as a Novel Multi-target Therapeutic Approach Against Chronic Pain
Frontiers in clinical drug research. CNS and neurological disorders·2022· 3 citedOpen Access
IMT504 blocks allodynia in rats with spared nerve injury by promoting the migration of mesenchymal stem cells and by favoring an anti-inflammatory milieu at the injured nerve
Pain·2021· 12 citedOpen Access
Intrathecal Administration of an Anti‐nociceptive Non-CpG Oligodeoxynucleotide Reduces Glial Activation and Central Sensitization
Journal of Neuroimmune Pharmacology·2021· 7 cited
Oligonucleotide IMT504 Improves Glucose Metabolism and Controls Immune Cell Mediators in Female Diabetic NOD Mice
Nucleic Acid Therapeutics·2020· 4 cited
IMT504 Provides Analgesia by Modulating Cell Infiltrate and Inflammatory Milieu in a Chronic Pain Model
Journal of Neuroimmune Pharmacology·2020· 12 cited
Contribution of neural crest and GLAST<sup>+</sup> Wnt1<sup>+</sup> bone marrow pericytes with liver fibrogenesis and/or regeneration
Liver International·2020· 10 citedOpen Access
Desarrollo y evaluación de prototipos de sustitutos óseos acelulares generados por bioingeniería de tejidos para resolución de lesiones críticas de hueso y osteogénesis guiada
2019
SAT-172 Continuous, Prolonged Treatment with the Oligonucleotide IMT504 in Diabetic NOD Mice Greatly Improves All Parameters of the Diabetic Condition
Journal of the Endocrine Society·2019Open Access
SAT-165 Does Oligodeoxynucleotide IMT504 Have Any Effect On Beta Cells? A Preliminary Study On MIN6B1 Cell Line
Journal of the Endocrine Society·2019Open Access
Long-lasting ameliorating effects of the oligodeoxynucleotide IMT504 on mechanical allodynia and hindpaw edema in rats with chronic hindpaw inflammation
Neuroscience Letters·2017· 12 cited
Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy
World Journal of Stem Cells·2017· 12 citedOpen Access
Proposed mechanisms for oligonucleotide IMT504 induced diabetes reversion in a mouse model of immunodependent diabetes
American Journal of Physiology-Endocrinology and Metabolism·2016· 3 citedOpen Access
PyNTTTTGT and CpG Immunostimulatory Oligonucleotides: Effect on Granulocyte/Monocyte Colony-Stimulating Factor (GM-CSF) Secretion by Human CD56+ (NK and NKT) Cells
PLoS ONE·2015· 16 citedOpen Access
Non-Clinical Safety Studies of IMT504, a Unique Non-CpG Oligonucleotide
Nucleic Acid Therapeutics·2014· 11 citedOpen Access
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Frequent Co-authors

Fernanda Elı́as(14), Juan M. Corchado(14), Jorge Zorzópulos(13), Juan Fló(12), Victoria Lux‐Lantos(11), Gustavo M. Somoza(10), Marcelo J. Villar(9), María Silvia Bianchi(9), Marı́a Florencia Coronel(8), Ricardo A. López(7), Norma Alejandra Chasseing(7), Carlos Libertun(7), Pablo R. Brumovsky(7), Andrés Hernando-Insúa(6), Candelaria Leiguarda(6), Julia Rubione(6), Jorge M. Affanni(5), Néstor Lago(5), Esteban Fiore(5), Jean Rivier(4)