Bernard Van Eerdenbrugh

Novartis (Switzerland) — Switzerland

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

26h-index3.8kcitations63works0.02yr avg
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Research Topics

Drug Solubulity and Delivery Systems(31), Crystallization and Solubility Studies(23), Analytical Chemistry and Chromatography(15), Protein purification and stability(10), Microencapsulation and Drying Processes(9)

Publications63 total

Evaluation of the Formulation Parameter-Dependent Redispersibility of API Nanoparticles from Fluid Bed Granules
Pharmaceutics·2022· 6 citedOpen Access
Abstract 1770: A new DOT1L inhibitor with <i>in vivo</i> activity in mouse models of MLL-translocated leukemia
Cancer Research·2020· 2 cited
Spray drying of API nanosuspensions: Importance of drying temperature, type and content of matrix former and particle size for successful formulation and process development
European Journal of Pharmaceutics and Biopharmaceutics·2020· 18 cited
Influence of Formulation Parameters on Redispersibility of Naproxen Nanoparticles from Granules Produced in a Fluidized Bed Process
Pharmaceutics·2020· 33 citedOpen Access
Spray 1 drying of API nanosuspensions: Importance of particle size, matrix former content and drying temperature for successful formulation and process development
The Novartis Repository (Novartis)·2020Open Access
New Potent DOT1L Inhibitors for <i>in Vivo</i> Evaluation in Mouse
ACS Medicinal Chemistry Letters·2019· 36 citedOpen Access
Ranking Itraconazole Formulations Based on the Flux through Artificial Lipophilic Membrane
Pharmaceutical Research·2018· 39 cited
Trends in the Precipitation and Crystallization Behavior of Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs Assessed Using Synchrotron Radiation
Journal of Pharmaceutical Sciences·2015· 88 citedOpen Access
W5093: Dissolution, free drug concentration and permeability of crystalline nanoparticle formulations: study using in situ fiber optic and potentiometric techniques
2015
Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments
Pharmaceutical Research·2013· 82 cited
Media and Additive Influences on the Amorphous Solubility of Ketoprofen
2013
Rapid Insight into Heating-Induced Phase Transformations in the Solid State of the Calcium Salt of Atorvastatin Using Multivariate Data Analysis
Pharmaceutical Research·2012· 22 cited
pH-Induced Precipitation Behavior of Weakly Basic Compounds: Determination of Extent and Duration of Supersaturation Using Potentiometric Titration and Correlation to Solid State Properties
Pharmaceutical Research·2012· 136 cited
Nanoscale Mid-Infrared Evaluation of the Miscibility Behavior of Blends of Dextran or Maltodextrin with Poly(vinylpyrrolidone)
Molecular Pharmaceutics·2012· 67 cited
Nanoscale Mid-Infrared Imaging of Phase Separation in a Drug–Polymer Blend
Journal of Pharmaceutical Sciences·2012· 85 cited
Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone)
Pharmaceutical Research·2012· 15 cited
Nanoscale Mid-Infrared Imaging for the Characterization of Pharmaceutical Systems
2012
Binary Blends of Poly(Vinylpyrrolidone) with Dextran and Maltodextrin as Model Systems for the Study of Miscibility
2012
Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Suspension
2012
Nanoscale Mid-Infrared Evaluation of the Miscibility Behavior of Blends of Dextran or Maltodextrin with Poly(vinylpyrrolidone)
Journal of the American Chemical Society·2012
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Frequent Co-authors

Patrick Augustijns(22), Lynne S. Taylor(22), Johan A. Martens(17), Guy Van den Mooter(16), Ludo Froyen(16), Jan Van Humbeeck(16), Jan Vermant(7), Michael Juhnke(5), Martin Wewers(4), Stefan Czyz(4), Jan Henrik Finke(4), Heike Bunjes(4), Arno Kwade(4), Guy Van den Mooter(4), Shweta A. Raina(3), Michael Lo(3), Kevin Kjoller(3), Curtis Marcott(3), Phillip E. Fanwick(3), Jared A. Baird(2)