Lena F. Burbulla

Munich Cluster for Systems Neurology — Germany

Medicine · Health Sciences

25h-index8.1kcitations50works3.32yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(34), Lysosomal Storage Disorders Research(11), Neurological diseases and metabolism(9), Mitochondrial Function and Pathology(8), Autophagy in Disease and Therapy(8)

Publications49 total

Mitochondrial specialization and signaling shape neuronal function
Trends in Neurosciences·2026Open Access
VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1-linked Parkinson’s disease neurons
2025Open Access
Are oligodendrocytes bystanders or drivers of Parkinson’s disease pathology?
PLoS Biology·2025· 9 citedOpen Access
Translational View on Therapeutic Strategies and Upcoming Issues: Stem Cell and Brain Organoid Approaches for Parkinson’s Disease Therapy
Neuromethods·2024
Genome-wide association study of copy number variations in Parkinson’s disease
2024· 2 citedOpen Access
Association of Body Mass Index and Parkinson Disease
Neurology·2024· 9 citedOpen Access
Peripheral Sphingolipids as Potential Biomarkers of Parkinson disease Including Sex-Related Differences (P3-11.007)
Neurology·2023· 2 cited
Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers
Movement Disorders·2023· 25 citedOpen Access
Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders
Neurobiology of Disease·2022· 94 citedOpen Access
The Interaction between <scp><i>HLA‐DRB1</i></scp> and Smoking in Parkinson's Disease Revisited
Movement Disorders·2022· 12 citedOpen Access
Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease
Neurology·2022· 64 citedOpen Access
Mitochondrial Phenotypes in Parkinson’s Diseases—A Focus on Human iPSC-Derived Dopaminergic Neurons
Cells·2021· 18 citedOpen Access
Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons
Scientific Reports·2021· 17 citedOpen Access
Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson’s Disease
Journal of Parkinson s Disease·2021· 67 citedOpen Access
Direct targeting of wild-type glucocerebrosidase by antipsychotic quetiapine improves pathogenic phenotypes in Parkinson’s disease models
JCI Insight·2021· 8 citedOpen Access
Modeling Brain Pathology of <scp>Niemann‐Pick</scp> Disease Type C Using Patient‐Derived Neurons
Movement Disorders·2021· 7 citedOpen Access
The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson’s Disease
Frontiers in Cell and Developmental Biology·2020· 87 citedOpen Access
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease
Science Translational Medicine·2020· 63 citedOpen Access
Gelator Length Precisely Tunes Supramolecular Hydrogel Stiffness and Neuronal Phenotype in 3D Culture
ACS Biomaterials Science & Engineering·2020· 47 citedOpen Access
Author Correction: Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain
Nature Neuroscience·2020· 3 citedOpen Access
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Frequent Co-authors

Dimitri Krainc(27), Rejko Krüger(22), Thomas Gasser(8), Kathrin Brockmann(7), Patrick May(7), Dirk Woitalla(6), Claudia Schulte(6), Manu Sharma(6), Cloé Domenighetti(6), Pierre‐Emmanuel Sugier(6), Ashwin Ashok Kumar Sreelatha(6), Peter Lichtner(6), Connor Edsall(6), George D. Mellick(6), Alexander Zimprich(6), Walter Pirker(6), Ekaterina Rogaeva(6), Anthony E. Lang(6), Pille Taba(6), Alexis Brice(6)