Kaori Sasai

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index1.5kcitations28works9.02yr avg
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Research Topics

Microtubule and mitosis dynamics(17), Cancer-related Molecular Pathways(8), Plant nutrient uptake and metabolism(7), DNA Repair Mechanisms(5), Epigenetics and DNA Methylation(4)

Publications28 total

eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
Science Signaling·2024· 9 citedOpen Access
Human NINEIN polymorphism at codon 1111 is associated with the risk of colorectal cancer
Biomedical Reports·2020· 4 citedOpen Access
Abstract LB-095: Aurora-A is elevated in cancer cells due to inactivation of EF1A2-PTEN-GSK3b regulated late S-G2 phase specific degradation pathway
Cancer Research·2019
Abstract LB-095: Aurora-A is elevated in cancer cells due to inactivation of EF1A2-PTEN-GSK3b regulated late S-G2 phase specific degradation pathway
Molecular and Cellular Biology / Genetics·2019
Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion
Cancer Letters·2019· 50 citedOpen Access
Abstract P1-05-05: eEF1A2 facilitates PTEN-GSK3β mediated Aurora-A protein degradation during S-G2 phase inactivated in PTEN-deficient breast cancer
Cancer Research·2019
Emerging role of hnRNP F in mitotic cell cycle progression.
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2017
Unique circulating microRNAs in relation to EGFR mutation status in Japanese smoker male with lung adenocarcinoma
Oncotarget·2017· 8 citedOpen Access
Human RAD 17 Polymorphism at Codon 546 Is Associated with the Risk of Colorectal Cancer.
PubMed·2017· 3 cited
Functional Significance of Aurora Kinases–p53 Protein Family Interactions in Cancer
Frontiers in Oncology·2016· 62 citedOpen Access
Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer
Carcinogenesis·2016· 27 citedOpen Access
Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex
PLoS ONE·2016· 26 citedOpen Access
BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition.
Journal of Biological Chemistry·2015· 3 citedOpen Access
Regulation of AURKC expression by CpG island methylation in human cancer cells
Tumor Biology·2015· 13 cited
93 PREDICTION OF RADIOSENSITIVITY USING PHOSPHORYLATION OF HISTONE H2AX
Radiotherapy and Oncology·2012
Aurora Kinase-A Inactivates DNA Damage-Induced Apoptosis and Spindle Assembly Checkpoint Response Functions of p73
Cancer Cell·2012· 84 citedOpen Access
Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells
Cell Cycle·2008· 67 citedOpen Access
Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality
Oncogene·2008· 71 citedOpen Access
Functional Significance of Aurora Kinase A in Centrosome Amplification and Genomic Instability
Advances in experimental medicine and biology·2008· 17 cited
Aurora‐A kinase phosphorylation of Aurora‐A kinase interacting protein (AIP) and stabilization of the enzyme‐substrate complex
Journal of Cellular Biochemistry·2007· 16 cited
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Frequent Co-authors

Hiroshi Katayama(19), Subrata Sen(17), Fumio Suzuki(7), Warapen Treekitkarnmongkol(7), Kazuharu Kai(5), Ayşegül A. Şahin(4), Ignacio I. Wistuba(4), Hirohiko Yajima(4), Hiromasa Yamamoto(3), Luisa M. Solis(3), Yoshimi Jitsumori(3), Alastair M. Thompson(3), Jonathan M. Lee(3), Kwong‐Kwok Wong(3), Catherine M. Abbott(3), Hiroshi Katayama(3), Sachio Ito(3), Akiko Sakai(3), Yoshimi Jltsumori(3), Lidong Qin(3)