Sophie Layé

Institut National de la Recherche Agronomique — MA

Nursing · Health Sciences

72h-index15.6kcitations372works3.52yr avg
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Research Topics

Fatty Acid Research and Health(111), Neuroinflammation and Neurodegeneration Mechanisms(78), Diet and metabolism studies(70), Tryptophan and brain disorders(47), Stress Responses and Cortisol(45)

Publications371 total

Maternal n-3 PUFA deficiency alters brain fatty acid and oxylipin profiles across perinatal development in offspring
2025Open Access
Preventing effect of plant extracts and omega-3 on age-related cognitive decline in male mice
Brain Behavior & Immunity - Health·2025Open Access
Rodent models of Alzheimer's disease: Critical analysis of current hypotheses and pathways for future research
Progress in Neurobiology·2025· 1 citedOpen Access
Fecal transplantation from humans with obesity to mice drives a selective microbial signature without impacting behavioral and metabolic health
Scientific Reports·2025· 4 citedOpen Access
Fructose malabsorption induces dysbiosis and increases anxiety in Human and animal models
2025· 1 citedOpen Access
Toward a better understanding of the relationship between docosahexaenoic acid and bronchopulmonary dysplasia and the questions that remain
American Journal of Clinical Nutrition·2025· 1 cited
Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention
Clinical Nutrition ESPEN·2025· 3 citedOpen Access
Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder
eLife·2024Open Access
Author response: Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder
2024Open Access
Inverse associations between plasma docosahexaenoic acid and pTau181 in the preclinical stages of Alzheimer’s disease
Brain Behavior and Immunity·2024
Inhibiting AMPA receptor signaling in oligodendrocytes rescues synapse loss in a model of autoimmune demyelination
iScience·2024· 2 citedOpen Access
Phénotypage multidimensionnel : intérêt de l’outil HDeeP
SPIRE - Sciences Po Institutional REpository·2024
Plant extracts and omega-3 supplementation modulate hippocampal oxylipin profile in response to LPS-induced neuroinflammation
Inflammation Research·2024· 4 citedOpen Access
Plant Extracts and ω-3 Improve Short-Term Memory and Modulate the Microbiota–Gut–Brain Axis in D-galactose Model Mice
Journal of Nutrition·2024· 6 citedOpen Access
Blockage of ATGL-mediated breakdown of lipid droplets in microglia alleviates neuroinflammatory and behavioural responses to lipopolysaccharides
Brain Behavior and Immunity·2024· 21 citedOpen Access
Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder
2024Open Access
Author response: Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder
2024Open Access
Plant extracts and omega-3 supplementation modulate hippocampal oxylipin profile in response to LPS-induced neuroinflammation
2024Open Access
Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer’s disease research
Neuroscience & Biobehavioral Reviews·2024· 12 citedOpen Access
Reviewer #1 (Public Review): Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with alcohol use disorder
2024Open Access
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Frequent Co-authors

Joffre Corinne(13), Robert Dantzer(12), Agnès Aubert(11), Patricia Parnet(10), Agnès Nadjar(10), Lucile Capuron(6), Nathalie Castanon(5), Guillaume Ferreira(5), Véronique De Smedt‐Peyrusse(5), Rose-Marie Bluthé(5), Keith W. Kelley(5), Charlotte Madore(5), Quentin Leyrolle(4), Thomas Larrieu(4), Jean-Christophe Delpech(4), Richard P. Bazinet(3), Emmanuelle Goujon(3), Julie Sauvant(3), François Labrousse(3), Lionel Brétillon(3)