Lauren A. Ford-Siltz

Center for Biologics Evaluation and Research — United States

Medicine · Health Sciences

16h-index921citations37works4.32yr avg
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Research Topics

Viral gastroenteritis research and epidemiology(29), Viral Infections and Immunology Research(16), Animal Virus Infections Studies(13), Virus-based gene therapy research(12), Respiratory viral infections research(5)

Publications37 total

Variable and conserved B cell epitopes of GII.4 human noroviruses
Journal of Virology·2026Open Access
GII.17 norovirus re-emerged in the 2020s as a result of dynamic and adaptive evolutionary processes
Nature Communications·2025· 5 citedOpen Access
The saga to monitor and control norovirus: the rise of GII.17
Journal of General Virology·2025· 12 citedOpen Access
Highly variable antigenic site located at the apex of GII.4 norovirus capsid protein induces cross-reactive blocking antibodies in a variant-specific manner
Journal of Virology·2025· 3 citedOpen Access
Manipulation of immunodominant variable epitopes of norovirus capsid protein elicited cross-blocking antibodies to different GII.4 variants despite the low potency of the polyclonal sera
Journal of Virology·2025· 3 citedOpen Access
GII.17 norovirus re-emerged in the 2020s as a result of dynamic and adaptive evolutionary processes
Figshare·2025Open Access
GII.17 norovirus re-emerged in the 2020s as a result of dynamic and adaptive evolutionary processes
Figshare·2025Open Access
Characterization of cross-reactive, non-neutralizing monoclonal antibodies against a pandemic GII.4 norovirus variant
Microbiology Spectrum·2024· 4 citedOpen Access
Antigenic Characterization of Novel Human Norovirus GII.4 Variants San Francisco 2017 and Hong Kong 2019
Emerging infectious diseases·2024· 11 citedOpen Access
Analysis of Archival Sera From Norovirus-Infected Individuals Demonstrates That Cross-Blocking of Emerging Viruses Is Genotype-Specific
The Journal of Infectious Diseases·2024· 5 citedOpen Access
Minimal Antigenic Evolution after a Decade of Norovirus GII.4 Sydney_2012 Circulation in Humans
Journal of Virology·2023· 46 citedOpen Access
Cross-reactive neutralizing human monoclonal antibodies mapping to variable antigenic sites on the norovirus major capsid protein
Frontiers in Immunology·2022· 15 citedOpen Access
Dynamic immunodominance hierarchy of neutralizing antibody responses to evolving GII.4 noroviruses
Cell Reports·2022· 40 citedOpen Access
Genome-wide analyses of human noroviruses provide insights on evolutionary dynamics and evidence of coexisting viral populations evolving under recombination constraints
PLoS Pathogens·2021· 65 citedOpen Access
Antigenic cartography reveals complexities of genetic determinants that lead to antigenic differences among pandemic GII.4 noroviruses
Proceedings of the National Academy of Sciences·2021· 49 citedOpen Access
Viral intra-host evolution in immunocompetent children contributes to human norovirus diversification at the global scale
Figshare·2021Open Access
Viral intra-host evolution in immunocompetent children contributes to human norovirus diversification at the global scale
Emerging Microbes & Infections·2021· 20 citedOpen Access
Viral intra-host evolution in immunocompetent children contributes to human norovirus diversification at the global scale
Figshare·2021Open Access
Understanding the relationship between norovirus diversity and immunity
Gut Microbes·2021· 62 citedOpen Access
Norovirus-specific immunoglobulin A in breast milk for protection against norovirus-associated diarrhea among infants
EClinicalMedicine·2020· 35 citedOpen Access
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Frequent Co-authors

Kentaro Tohma(30), Gabriel I. Parra(29), Joseph A. Kendra(14), Cara J. Lepore(13), Kelsey A. Pilewski(10), Mayuko Saito(9), Holger Mayta(9), Robert H. Gilman(9), Yamei Gao(7), Michael Landivar(7), Mirko Zimic(6), George A. Belov(6), Mónica J. Pajuelo(5), Ekaterina G. Viktorova(4), Jules Nchoutmboube(4), Sandra Niendorf(4), Gerardo Sánchez(3), William E. De La O(3), Juan Ignacio Degiuseppe(2), Juan A. Stupka(2)