Isabelle Sponne

Institut National de Recherche et de Sécurité — France

Medicine · Health Sciences

13h-index1.2kcitations24works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(6), Contact Dermatitis and Allergies(4), Prion Diseases and Protein Misfolding(4), Immunotoxicology and immune responses(4), Chromium effects and bioremediation(3)

Publications24 total

P29-11 A delayed activation of p38 MAPK in dendritic cells distinguishes respiratory from skin sensitizers
Toxicology Letters·2025
The <scp>BMDC</scp> model, a performant cell‐based test to assess the sensitizing potential and potency of chemicals including pre/pro‐haptens
Contact Dermatitis·2023· 7 citedOpen Access
A new cytometry-based method reveals an accumulation of Nrf2 in dendritic cells exposed to two respiratory sensitizers
Toxicology Research·2021· 2 citedOpen Access
De nouveaux tests pour évaluer le caractère sensibilisant d’une substance industrielle
Archives des maladies professionnelles et de médecine du travail/Archives des maladies professionnelles et de l'environnement·2020
Biohazards - INRS Scientific Conference, Nancy, 5 - 7 June 2019
HAL (Le Centre pour la Communication Scientifique Directe)·2019Open Access
Activation of T cells by dendritic cells exposed to a reference sensitizer: Towards a promising model to assess the allergenic potential of chemicals
Contact Dermatitis·2018· 7 cited
Development of an exposure indicator to hexavalent chromium: An in vitro evaluation with human blood
Toxicology Letters·2017· 1 cited
<i>In vitro</i> detection of chemical allergens: an optimized assay using mouse bone marrow‐derived dendritic cells
Contact Dermatitis·2017· 15 cited
Can chromium in red blood cells be used as an indicator of exposure to hexavalent chromium? An in vitro investigation
Toxicology Letters·2016
Evaluation of chromium in red blood cells as an indicator of exposure to hexavalent chromium: An in vitro study
Toxicology Letters·2016· 46 citedOpen Access
H2S induced hypometabolism in mice is missing in sedated sheep
Respiratory Physiology & Neurobiology·2007· 101 cited
ALTERED KINETICS OF HYPOXIA INDUCED HYPOMETABOLISM IN LEPTIN DEFICIENT MICE
The FASEB Journal·2007
Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway
Neurobiology of Disease·2006· 217 citedOpen Access
Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid‐β oligomers
Journal of Neurochemistry·2005· 129 cited
Microtubule-associated Protein MAP1A, MAP1B, and MAP2 Proteolysis during Soluble Amyloid β-Peptide-induced Neuronal Apoptosis
Journal of Biological Chemistry·2005· 115 citedOpen Access
Cytosolic phospholipase A <sub>2</sub> mediates neuronal apoptosis induced by soluble oligomers of the amyloid‐β peptide
The FASEB Journal·2004· 145 cited
Membrane cholesterol interferes with neuronal apoptosis induced by soluble oligomers but not fibrils of the amyloid‐β peptide
The FASEB Journal·2004· 85 cited
Oligodendrocytes are susceptible to apoptotic cell death induced by prion protein‐derived peptides
Glia·2004· 6 cited
Humanin rescues cortical neurons from prion-peptide-induced apoptosis
Molecular and Cellular Neuroscience·2003· 68 cited
<i>In Vivo</i>and<i>In Vitro</i>Neurotoxicity of the Human Prion Protein (PrP) Fragment P118–135 Independently of PrP Expression
Journal of Neuroscience·2003· 49 citedOpen Access
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Frequent Co-authors

Thierry Pillot(10), Violette Koziel(8), Samuel Müller(8), Badreddine Kriem(7), Jean‐Luc Olivier(7), Thierry Oster(7), Alexandre Fifre(7), Fabrice Battais(6), Isabelle Langonné(6), Bernard E. Bihain(5), Julianne Mathiot(5), Adrien Audry(4), Catherine Malaplate‐Armand(3), Jérôme Devoy(3), Mathieu Melczer(3), Aurélie Remy(3), Amélie Coiscaud(3), Ihsen Youssef(2), Brigitte Leininger‐Muller(2), Frances T. Yen(2)