Wieger Hemrika

Chemistry · Physical Sciences

26h-index2.6kcitations55works3.02yr avg
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Research Topics

Vanadium and Halogenation Chemistry(15), Metal-Catalyzed Oxygenation Mechanisms(12), Photosynthetic Processes and Mechanisms(7), Mitochondrial Function and Pathology(6), Wnt/β-catenin signaling in development and cancer(5)

Publications55 total

Broad Epitope Coverage of Therapeutic Multi-Antibody Combinations Targeting SARS-CoV-2 Boosts In Vivo Protection and Neutralization Potency to Corner an Immune-Evading Virus
Biomedicines·2024· 3 citedOpen Access
Structure and Physiological Function of Vanadium Chloroperoxidase
2022· 4 cited
Cornering an Ever-Evolving Coronavirus: TATX-03, a fully human synergistic multi-antibody cocktail targeting the SARS-CoV-2 Spike Protein with <i>in vivo</i> efficacy
2021· 3 cited
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
Cell stem cell·2020· 148 citedOpen Access
Combining somatic mutations present in different<i>in vivo</i>affinity-matured antibodies isolated from immunized<i>Lama glama</i>yields ultra-potent antibody therapeutics
Protein Engineering Design and Selection·2016· 14 citedOpen Access
免疫されたLama glamaから分離された異なるin vivo親和性成熟抗体に存在する体細胞突然変異の組合せは超強力な抗体治療をもたらす
Protein Engineering Design and Selection·2016
Structure of Interleukin-6 in complex with a Camelid Fab fragment
2014· 1 cited
Assessment of the Antiviral Properties of Recombinant Porcine SP-D against Various Influenza A Viruses In Vitro
PLoS ONE·2011· 30 citedOpen Access
Introduction of N-Linked Glycans in the Lectin Domain of Surfactant Protein D
Journal of Biological Chemistry·2011· 23 citedOpen Access
Gonadotropins and spermatogenesis in Zebrafish
DIGITAL.CSIC (Spanish National Research Council (CSIC))·2010
Studies in Zebrafish Reveal Unusual Cellular Expression Patterns of Gonadotropin Receptor Messenger Ribonucleic Acids in the Testis and Unexpected Functional Differentiation of the Gonadotropins
Endocrinology·2010· 143 citedOpen Access
Unexpected Functional Differentiation of the Gonadotropins Gonadotropin Receptor Messenger Ribonucleic Acids in the Testis and Studies in Zebrafish Reveal Unusual Cellular Expression Patterns of
2010
Structure and functional relevance of the Slit2 homodimerization domain
EMBO Reports·2009· 40 citedOpen Access
Staphylococcal Superantigen-like 10 Inhibits CXCL12-Induced Human Tumor Cell Migration
Neoplasia·2009· 76 citedOpen Access
Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood·2008· 87 citedOpen Access
In vitro and in vivo bioactivity of recombinant canine hepatocyte growth factor
The Veterinary Journal·2008· 6 cited
Chicken lung lectin is a functional C-type lectin and inhibits haemagglutination by influenza A virus
Veterinary Microbiology·2008· 33 citedOpen Access
cGMP-binding Prepares PKG for Substrate Binding by Disclosing the C-terminal Domain
Journal of Molecular Biology·2007· 73 cited
Structural insights into the Slit-Robo complex
Proceedings of the National Academy of Sciences·2007· 182 citedOpen Access
Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3
Acta Crystallographica Section D Biological Crystallography·2007· 20 cited
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Frequent Co-authors

Ron Wever(14), Roland A. Romijn(13), Rokus Renirie(9), Phil Barnett(8), Piet Gros(6), Lukas Dekker(6), J.A. Berden(6), S. Cusack(4), Andrew A. McCarthy(4), Eric G. Huizinga(4), Cécile Morlot(3), Albrecht Messerschmidt(3), Fin J. Milder(3), Mohamed R. Daha(3), Leslie A. Grivell(3), Martin van Eijk(3), Henk P. Haagsman(3), Henk F. Tabak(2), Tjalling Siersma(2), Janynke F. Brons(2)