Alan Aderem

Center for Infectious Disease Research — United States

Immunology and Microbiology · Life Sciences

104h-index52.5kcitations291works9.62yr avg
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Research Topics

Immune Response and Inflammation(84), interferon and immune responses(42), Immune Cell Function and Interaction(35), Protein Kinase Regulation and GTPase Signaling(25), Immune cells in cancer(25)

Publications291 total

Author Correction: CD8+ T cells induce cachexia during chronic viral infection
Nature Immunology·2025Open Access
Early and opposing neutrophil and CD4 T cell responses shape pulmonary tuberculosis pathology
The Journal of Experimental Medicine·2025· 10 citedOpen Access
APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps
PLoS Pathogens·2025· 6 citedOpen Access
Absence of c-Maf and IL-10 enables type I IFN enhancement of innate responses to LPS in alveolar macrophages
The Journal of Immunology·2025· 5 citedOpen Access
APOE Protects Against Severe Infection with <i>Mycobacterium tuberculosis</i> by Restraining Production of Neutrophil Extracellular Traps
2024Open Access
Oxysterol binding protein regulates the resolution of TLR-induced cytokine production in macrophages
Proceedings of the National Academy of Sciences·2024· 7 citedOpen Access
Host and pathogen genetic diversity shape vaccine-mediated protection to Mycobacterium tuberculosis
Frontiers in Immunology·2024· 11 citedOpen Access
Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages
2024· 1 citedOpen Access
CD4-mediated immunity shapes neutrophil-driven tuberculous pathology
2024· 9 citedOpen Access
Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection
PLoS Pathogens·2024· 47 citedOpen Access
Exposure to <i>mycobacterium</i> remodels alveolar macrophages and the early innate response to <i>Mycobacterium tuberculosis</i> infection
2022· 3 citedOpen Access
Genetic Modification of Primary Human Myeloid Cells to Study Cell Migration, Activation, and Organelle Dynamics
Current Protocols·2022· 8 citedOpen Access
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection
Cell chemical biology·2022· 23 citedOpen Access
Type I interferon decreases macrophage energy metabolism during mycobacterial infection
Cell Reports·2021· 126 citedOpen Access
ILF3 Is a Negative Transcriptional Regulator of Innate Immune Responses and Myeloid Dendritic Cell Maturation
The Journal of Immunology·2021· 25 citedOpen Access
Use of a Contained <i>Mycobacterium tuberculosis</i> Mouse Infection Model to Predict Active Disease and Containment in Humans
The Journal of Infectious Diseases·2021· 9 citedOpen Access
Caspase-1-induced pyroptotic cell death
UNC Libraries·2020Open Access
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium
UNC Libraries·2020Open Access
Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19
Cell·2020· 625 citedOpen Access
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
The Journal of Cell Biology·2020· 27 citedOpen Access
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Frequent Co-authors

Kelly D. Smith(10), David M. Underhill(9), Adrian Ozinsky(8), Edward A. Miao(8), Daniel E. Zak(5), Fumitaka Hayashi(4), Thomas R. Hawn(4), Kathleen A. Kennedy(4), Adeline M. Hajjar(3), Christopher B. Wilson(3), Irina A. Leaf(3), Dat P. Mao(3), Monica Dors(3), Sarah Warren(3), Eva K. Lee(3), Helder I. Nakaya(3), Rafi Ahmed(3), Bali Pulendran(3), Erica Andersen‐Nissen(3), Lee‐Ann H. Allen(3)