Vasco Meneghini

Vita-Salute San Raffaele University — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.1kcitations33works10.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

CRISPR and Genetic Engineering(10), Hemoglobinopathies and Related Disorders(7), Pluripotent Stem Cells Research(5), Neurogenesis and neuroplasticity mechanisms(5), Virus-based gene therapy research(5)

Publications33 total

AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain
Nature Communications·2025· 18 citedOpen Access
Human iPSC-derived neural stem cells displaying radial glia signature exhibit long-term safety in mice
Nature Communications·2024· 10 citedOpen Access
AAV vectors trigger DNA damage responses and STING-dependent inflammation in human CNS cells
2024· 2 citedOpen Access
Human iPSC-derived neural stem cells display a radial glia-like signature <i>in vitro</i> and favorable long-term safety in transplanted mice
2023· 1 citedOpen Access
Editorial: Ex-vivo and in-vivo genome engineering for metabolic and neurometabolic diseases
Frontiers in Genome Editing·2023· 2 citedOpen Access
In vivo Gene Therapy to the Liver and Nervous System: Promises and Challenges
Frontiers in Medicine·2022· 9 citedOpen Access
Intracerebroventricular transplantation of human iPSC-derived neural stem cells (hiPSC-NSCs) into neonatal mice
Methods in cell biology·2022· 4 cited
Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease
Molecular Therapy·2021· 12 citedOpen Access
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System
Frontiers in Genome Editing·2021· 31 citedOpen Access
Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases
Frontiers in Molecular Biosciences·2020· 20 citedOpen Access
GATA Factor-Mediated Gene Regulation in Human Erythropoiesis
iScience·2020· 34 citedOpen Access
Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype
Science Advances·2020· 131 citedOpen Access
Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes
Blood·2019
Optimization of CRISPR/Cas9 Delivery to Human Hematopoietic Stem and Progenitor Cells for Therapeutic Genomic Rearrangements
Molecular Therapy·2018· 129 citedOpen Access
An Optimized Lentiviral Vector Efficiently Corrects the Human Sickle Cell Disease Phenotype
Molecular Therapy — Methods & Clinical Development·2018· 30 citedOpen Access
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy
Cell Death and Disease·2018· 47 citedOpen Access
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus
Blood·2018· 184 citedOpen Access
Transcription Factors CREB and NF-KB: Involvement in Synaptic Plasticity and Memory Formation
2018· 1 cited
Induction of Fetal Hemoglobin Synthesis By Crispr/Cas9-Mediated Disruption of the β-Globin Locus Architecture
Blood·2016· 1 cited
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy
Stem Cells Translational Medicine·2016· 84 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Angela Gritti(12), Annarita Miccio(11), Tristan Félix(8), Mario Amendola(7), Marina Cavazzana(7), Fulvio Mavilio(7), Marco Luciani(7), Chiara Antoniani(6), Annalisa Lattanzi(6), Leslie Weber(6), Mariagrazia Grilli(6), Francesco Morena(5), Sabata Martino(5), Elisa Magrin(4), Giulia Pavani(4), Matthew H. Porteus(4), Wassim El Nemer(4), Giacomo Frati(4), Cécile Masson(4), Ivan Merelli(4)