Frank Schweizer

University of Manitoba — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

43h-index8.1kcitations194works2.32yr avg
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Research Topics

Antibiotic Resistance in Bacteria(72), Carbohydrate Chemistry and Synthesis(53), Glycosylation and Glycoproteins Research(42), Antimicrobial Peptides and Activities(40), Chemical Synthesis and Analysis(39)

Publications194 total

Structure–Activity and Cationic Amphiphilic Drug-like Behavior of Aromatic Triamino Glycosylated Antitumor Ether Lipids with Cytotoxicity in 2D and 3D Models
ACS Medicinal Chemistry Letters·2025Open Access
Investigating the adjuvant activity of the proline-rich antimicrobial lipopeptide C12-PRP against antimicrobial-resistant veterinary bacterial isolates
Journal of Global Antimicrobial Resistance·2025Open Access
Noncytotoxic polymyxin derivatives enhance antibiotic action against multidrug-resistant Gram-negative bacteria
Antimicrobial Agents and Chemotherapy·2025Open Access
Development of polymyxin- and aminoglycoside-based outer membrane permeabilizers: a review
Frontiers in Microbiology·2025· 1 citedOpen Access
Gram-positive pathogens from Canadian hospitals: 17 years of results from the CANWARD study (2007–23)
Journal of Antimicrobial Chemotherapy·2025
Gram-negative pathogens from Canadian hospitals: 17 years of results from the CANWARD study (2007–23)
Journal of Antimicrobial Chemotherapy·2025· 2 cited
Amphiphilic nebramine analogs synergize with β-lactam/β-lactamase inhibitor combinations, including cefepime–taniborbactam and meropenem–xeruborbactam against metallo-β-lactamase-carrying <i>Pseudomonas aeruginosa</i>
RSC Medicinal Chemistry·2025Open Access
Modulating polybasic character of galactose-based glycosylated antitumor ether lipids for enhanced cytotoxic response
RSC Medicinal Chemistry·2024· 1 citedOpen Access
Electrochemical Detection of Tobramycin Resistance in Escherichia Coli
Journal of The Electrochemical Society·2024
Cefepime–Taniborbactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination
Drugs·2024· 17 cited
Electrochemical Detection of Tobramycin Retention in E. coli Bacteria
ECS Meeting Abstracts·2024
Sulfonamide Bioisosteres of Niclosamide Enhance Antibacterial Activity of Colistin and Bacitracin
ChemMedChem·2024· 1 citedOpen Access
Exploring Structure–Activity Relationships of Niclosamide-Based Colistin Potentiators in Colistin-Resistant Gram-Negative Bacteria
Antibiotics·2024· 6 citedOpen Access
Application of tobramycin benzyl ether as an antibiotic adjuvant capable of sensitizing multidrug-resistant Gram-negative bacteria to rifampicin
RSC Medicinal Chemistry·2024· 4 citedOpen Access
Enhancing outer membrane permeability of tetracycline antibiotics in <i>P. aeruginosa</i> using TOB–CIP conjugates
RSC Medicinal Chemistry·2024· 2 citedOpen Access
Guanidinylated Amphiphilic Tobramycin Derivatives Synergize with β-Lactam/β-Lactamase Inhibitor Combinations against <i>Pseudomonas aeruginosa</i>
ACS Infectious Diseases·2023· 7 cited
Trimeric Tobramycin/Nebramine Synergizes β-Lactam Antibiotics against <i>Pseudomonas aeruginosa</i>
ACS Omega·2023· 4 citedOpen Access
Exploring Antibiotic-Potentiating Effects of Tobramycin–Deferiprone Conjugates in Pseudomonas aeruginosa
Antibiotics·2023· 5 citedOpen Access
Amphiphilic tribasic galactosamines potentiate rifampicin in Gram-negative bacteria at low Mg++/Ca++concentrations
Bioorganic & Medicinal Chemistry Letters·2023· 1 cited
Chimeric Tobramycin-Based Adjuvant TOB-TOB-CIP Potentiates Fluoroquinolone and β-Lactam Antibiotics against Multidrug-Resistant <i>Pseudomonas aeruginosa</i>
ACS Infectious Diseases·2023· 11 cited
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Frequent Co-authors

George G. Zhanel(42), James A. Karlowsky(20), Heather J. Adam(17), Philippe Lagacé‐Wiens(17), Andrew Walkty(16), Sheryl Zelenitsky(13), Daryl J. Hoban(13), Alfred S. Gin(10), Joseph P. Lynch(10), Ronald Domalaon(10), Alyssa Golden(9), Bala Kishan Gorityala(8), Ethan Rubinstein(7), Temilolu Idowu(6), Michael A. Zhanel(6), Smritilekha Bera(6), Andrew Denisuik(5), Courtney K. Lawrence(5), Brandon Findlay(5), Kimberly A. Nichol(5)