Abishek Iyer

Australian Research Council — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index3.1kcitations59works4.02yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(12), Immune cells in cancer(8), Complement system in diseases(7), Epigenetics and DNA Methylation(6), Adipokines, Inflammation, and Metabolic Diseases(6)

Publications59 total

A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis
British Journal of Pharmacology·2024· 4 citedOpen Access
PAR2 activation on human tubular epithelial cells engages converging signaling pathways to induce an inflammatory and fibrotic milieu
Frontiers in Pharmacology·2024· 4 citedOpen Access
Small Molecule Anti-Inflammatory TYK2 Inhibitors Attenuate Inflammation and Clinical Symptoms in a Mouse Model of Imiquimod Induced Psoriasis
Journal of Pharmacology and Experimental Therapeutics·2023· 1 citedOpen Access
Topical selective TYK2 inhibition attenuates inflammation and clinical symptoms in a mouse model of human psoriasis
The Journal of Immunology·2023Open Access
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages
Proceedings of the National Academy of Sciences·2023· 20 citedOpen Access
Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles
Journal of Medicinal Chemistry·2022· 7 citedOpen Access
Targeting Tumour-Associated Fibroblasts in Cancers
Frontiers in Oncology·2022· 29 citedOpen Access
Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation
Cell Reports·2022· 3 citedOpen Access
PAR2-Induced Tissue Factor Synthesis by Primary Cultures of Human Kidney Tubular Epithelial Cells Is Modified by Glucose Availability
International Journal of Molecular Sciences·2021· 7 citedOpen Access
Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines
PLoS ONE·2021· 4 citedOpen Access
PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting
Frontiers in Physiology·2021· 10 citedOpen Access
Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
Cell Reports·2020· 89 citedOpen Access
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity
Journal of Medicinal Chemistry·2020· 33 citedOpen Access
Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages
Frontiers in Immunology·2019· 37 citedOpen Access
Inhibitors of class I histone deacetylases attenuate thioacetamide‐induced liver fibrosis in mice by suppressing hepatic type 2 inflammation
British Journal of Pharmacology·2019· 33 citedOpen Access
Crystal Structures of Protein-Bound Cyclic Peptides
Chemical Reviews·2019· 103 citedOpen Access
Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation
The FASEB Journal·2019
Heterocycles for switching GPCR ligand conformation and activity
Queensland's institutional digital repository (The University of Queensland)·2019
Supplementary Figure S1 for AJP-Renal submission
UQ eSpace·2019
Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes
JCI Insight·2018· 49 citedOpen Access
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Frequent Co-authors

David P. Fairlie(32), Lindsay Brown(24), Robert C. Reid(16), Matthew J. Sweet(14), Junxian Lim(10), Jacky Y. Suen(7), Rink‐Jan Lohman(6), Glenda C. Gobé(5), Kaustav Das Gupta(5), Melanie R. Shakespear(5), Praveer Gupta(5), David A. Vesey(5), Andrew Fenning(4), Vernon Seow(4), Daniel M. Hohenhaus(4), Kate Schroder(4), Divya Ramnath(4), Jennifer L. Stow(4), Zhixuan Loh(4), David W. Johnson(4)