Radoslav I. Enchev

The Francis Crick Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.7kcitations39works1.72yr avg
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Research Topics

Ubiquitin and proteasome pathways(19), DNA Repair Mechanisms(6), Microtubule and mitosis dynamics(5), Endoplasmic Reticulum Stress and Disease(5), Protein Degradation and Inhibitors(5)

Publications39 total

Structural basis of CSN-mediated SCF deneddylation
Nature Communications·2026Open Access
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
Molecular Cell·2026Open Access
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome
Nature Communications·2025· 1 citedOpen Access
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
2025· 3 citedOpen Access
Chronobot: Deep learning guided time-resolved cryo-EM captures molecular choreography of RecA in homology search
2025· 2 citedOpen Access
Structural Basis of CSN-mediated SCF Deneddylation
2025Open Access
HSC70 coordinates COP9 signalosome and SCF ubiquitin ligase activity to enable a prompt stress response
EMBO Reports·2025· 3 citedOpen Access
Retraction Note: A mechanism for the suppression of homologous recombination in G1 cells
Nature·2025Open Access
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome
2024· 5 citedOpen Access
Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange
Molecular Cell·2023· 21 citedOpen Access
Structural dynamics: review of time-resolved cryo-EM
Acta Crystallographica Section D Structural Biology·2022· 50 citedOpen Access
Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation
Molecular Cell·2021· 30 citedOpen Access
Single-Molecule Investigation of Rad-51 Presynaptic Filament Assembly and the Role of Mediator Proteins
Biophysical Journal·2021Open Access
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
Molecular Cell·2021· 76 citedOpen Access
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
2020· 9 citedOpen Access
Modular microfluidics enables kinetic insight from time-resolved cryo-EM
Nature Communications·2020· 103 citedOpen Access
Visual Biochemistry: modular microfluidics enables kinetic insight from time-resolved cryo-EM
2020· 3 citedOpen Access
CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases
Cell Death and Differentiation·2019· 25 citedOpen Access
A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body–like pathology
Science Translational Medicine·2019· 39 citedOpen Access
CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases
2018· 1 citedOpen Access
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Frequent Co-authors

Matthias Peter(21), Märt-Erik Mäeots(8), Anne Schreiber(7), Florian Stengel(6), Ruedi Aebersold(5), Edward P. Morris(4), Shan Ding(4), Gabija Jurkeviciute(4), Anna Ulbricht(3), da Fonseca(3), Ruzbeh Mosadeghi(3), Kurt M. Reichermeier(3), Martin Winkler(3), Justin M. Reitsma(3), Yaru Zhang(3), Junyue Cao(3), Michael J. Sweredoski(3), Sonja Hess(3), Alexander Leitner(3), Raymond J. Deshaies(3)