Amer Alam

Medicine · Health Sciences

17h-index2.3kcitations33works3.72yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(10), Ion channel regulation and function(8), Lipid Membrane Structure and Behavior(7), Cholesterol and Lipid Metabolism(5), Nanoparticle-Based Drug Delivery(3)

Publications33 total

Structural insights into binding-site access and ligand recognition by human ABCB1
The EMBO Journal·2025· 9 citedOpen Access
Use of Bicelle-Generated Lipid Bilayer Vesicle Nanoparticles for In Vitro Measurement of Lipid Intermembrane Transport
Methods in molecular biology·2024
Structural insight into binding site access and ligand recognition by human ABCB1
2024· 2 citedOpen Access
Structure and Mechanism of Human ABC Transporters
Annual Review of Biophysics·2023· 156 citedOpen Access
<scp>Cryo‐EM</scp> structures of human <scp>ABCA7</scp> provide insights into its phospholipid translocation mechanisms
The EMBO Journal·2022· 24 citedOpen Access
Structural insights into a novel collapsed confirmation of human ABCB1 in a lipid environment
Acta Crystallographica Section A Foundations and Advances·2022Open Access
Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
Communications Biology·2022· 21 citedOpen Access
Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment
2021· 1 citedOpen Access
ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation
Frontiers in Neuroscience·2021· 21 citedOpen Access
Capturing the interplay of membrane lipids and structural transitions in human ABCA7
2021· 4 citedOpen Access
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1
Proceedings of the National Academy of Sciences·2020· 239 citedOpen Access
Rapid purification of HRV3C and TEV proteases using polyhistidine and polylysine tags
Korean Society for Structural Biology·2020· 2 cited
Measuring Lipid Transfer Protein Activity Using Bicelle-Dilution Model Membranes
Analytical Chemistry·2020· 7 citedOpen Access
Structure of the human lipid exporter ABCB4 in a lipid environment
Nature Structural & Molecular Biology·2019· 83 citedOpen Access
Online Payment Channel (epay)
2019
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein
Science·2019· 453 citedOpen Access
Nanodisc reconstituted human ABCB1 in complex with UIC2 fab and taxol
2019
Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1
Proceedings of the National Academy of Sciences·2018· 191 citedOpen Access
Structural basis of transcobalamin recognition by human CD320 receptor
Nature Communications·2016· 55 citedOpen Access
Structural studies of ion selectivity in tetrameric cation channels
The Journal of General Physiology·2011· 55 citedOpen Access
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Frequent Co-authors

Le Thi My Le(9), Kaspar P. Locher(7), Youxing Jiang(7), Phuoc Xuan Dang(5), Julia Kowal(4), James R. Thompson(4), Yu‐Cheng Jiang(4), Ning Shi(3), Devanshu Kurre(3), Eugenia V. Broude(2), Igor B. Roninson(2), M.G. Derebe(2), Weizhong Zeng(2), Jae‐Sung Woo(2), Sepehr Dehghani‐Ghahnaviyeh(2), Shashank Pant(2), Takahisa Kanikeyo(2), Emad Tajkhorshid(2), Janarjan Bhandari(2), Varun V. Gadkari(2)