George Scangos

VIR Biotechnology (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index3.8kcitations51works0.02yr avg
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Research Topics

Virus-based gene therapy research(19), CRISPR and Genetic Engineering(11), Animal Genetics and Reproduction(11), RNA Interference and Gene Delivery(9), Herpesvirus Infections and Treatments(6)

Publications49 total

Breakdown of �Tolerance� in the Natural Killer Interaction with H-2 Syngeneic Grafts
2015
Proceeding in a receding economy
Nature Biotechnology·2009· 1 cited
Differential effects on T cell and NK cell development by tissue-specific expression of H-2Dd transgene
European Journal of Immunology·2000
Differential effects on T cell and NK cell development by tissue-specific expression of H-2Dd transgene
European Journal of Immunology·2000· 4 citedOpen Access
Developmental biology's impact on drug development
Nature Biotechnology·1998
Drug discovery in the postgenomic era
Nature Biotechnology·1997· 16 cited
Basic and clinical models for Alzheimer's disease
European Neuropsychopharmacology·1992
<i>Response</i> : Age-Associated Inclusions in Normal and Transgenic Mouse Brain
Science·1992· 15 cited
Deposits of Amyloid β Protein in the Central Nervous System of Transgenic Mice
Science·1991· 140 cited
Regulatory region of human amyloid precursor protein (APP) gene promotes neuron-specific gene expression in the CNS of transgenic mice.
The EMBO Journal·1991· 69 citedOpen Access
Regulation and genetic control of brain amyloid
Brain Research Reviews·1991· 21 cited
Cell type-specific Expression of JC Virus T Antigen in Primary and Established Cell Lines from Transgenic Mice
Journal of General Virology·1990· 12 cited
Prevention of Allogeneic Bone Marrow Graft Rejection by H-2 Transgene in Donor Mice
Science·1989· 211 cited
EXPRESSION OF THE HUMAN AMYLOID PERCURSOR PROTEIN GENE IN THE CHS OF TRANSGENIC MICE
Journal of Neuropathology & Experimental Neurology·1989
The visna virus long terminal repeat directs expression of a reporter gene in activated macrophages, lymphocytes, and the central nervous systems of transgenic mice
Journal of Virology·1989· 58 citedOpen Access
Extinction of JC virus tumor-antigen expression in glial cell--fibroblast hybrids.
Proceedings of the National Academy of Sciences·1988· 22 citedOpen Access
Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice.
The Journal of Experimental Medicine·1988· 111 citedOpen Access
Containing the Early Region of )C Virus
1988
Dysmyelination in Transgenic Mice Containing the Early Region of JC Virus
1988· 3 cited
Dysmyelination in transgenic mice containing JC virus early region
Annals of Neurology·1988· 95 cited
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Frequent Co-authors

Charles J. Bieberich(12), Gregory D. Jay(11), Judy A. Small(11), Bruce D. Trapp(8), F.H. Ruddle(7), Barbara A. Christy(6), Frank H. Ruddle(5), D O Wirak(5), Axel Unterbeck(5), Kenneth Huttner(5), Petter Höglund(4), Klas Kärre(4), Richard M. Bayney(4), Takayuki Yoshioka(4), John Hart(3), Diane K. Juricek(3), Alan H. Beggs(3), J A Barbosa(2), Abraham Loyter(2), Claes Öhlén(2)