Peter Vella

Karolinska Institutet — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index379citations12works0.02yr avg
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Research Topics

Antibiotic Resistance in Bacteria(7), Tuberculosis Research and Epidemiology(4), Pharmaceutical and Antibiotic Environmental Impacts(2), Antibiotics Pharmacokinetics and Efficacy(2), Pneumocystis jirovecii pneumonia detection and treatment(2)

Publications12 total

A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens
Bioorganic & Medicinal Chemistry·2020· 22 citedOpen Access
Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium
Journal of Molecular Biology·2018· 42 citedOpen Access
Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1
European Journal of Medicinal Chemistry·2016· 43 citedOpen Access
Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans
JBIC Journal of Biological Inorganic Chemistry·2013· 37 cited
ChemInform Abstract: Synthesis and Kinetic Testing of New Inhibitors for a Metallo‐β‐lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa.
ChemInform·2012
The development of new drug leads to combat bacterial resistance towards antibiotics
Journal of Steroid Biochemistry·2012
3-Mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors
Bioorganic & Medicinal Chemistry Letters·2011· 67 citedOpen Access
Synthesis and kinetic testing of new inhibitors for a metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa
European Journal of Medicinal Chemistry·2011· 57 citedOpen Access
The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening
Bioorganic & Medicinal Chemistry Letters·2011· 72 cited
Tartrate-Resistant Acid Phosphatase: A Target for Anti-Osteoporotic Chemotherapeutics
Current Enzyme Inhibition·2010· 6 cited
Inhibition of purple acid phosphatase with α-alkoxynaphthylmethylphosphonic acids
Bioorganic & Medicinal Chemistry Letters·2008· 33 citedOpen Access
Ferredoxin–NADP+ reductases of Apicomplexa: unique properties of protozoan plant–type enzymes
2008

Frequent Co-authors

Gerhard Schenk(8), Ross P. McGeary(8), Waleed M. Hussein(5), David L. Ollis(3), Eleanor W. W. Leung(2), Nataša Mitić(2), Mosaad S. Mohamed(2), Rania H. Abd El‐Hameed(2), R. Schnell(2), G. Schneider(2), Daniel Clayton(1), Faridoon(1), Nazar Ul Islam(1), Omid Khalili Arjomandi(1), Yusralina Yusof(1), Hanna E. Sidjabat(1), Lei Sun(1), Anna Polyakova(1), Gleb Bourenkov(1), Fengyang Li(1)