Santos A. Susín

Délégation Paris 5 — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

77h-index34.5kcitations171works1.52yr avg
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Research Topics

Cell death mechanisms and regulation(95), Mitochondrial Function and Pathology(46), Chronic Lymphocytic Leukemia Research(28), RNA Interference and Gene Delivery(27), Phagocytosis and Immune Regulation(23)

Publications171 total

Olaparib sensitizes chronic lymphocytic leukemia to BTK- and BCL2-targeted therapies via PARP1-independent mitochondrial metabolic dysfunction
Leukemia·2026
REL overexpression and sustained NF-κB signaling associated with 2p gain induce resistance to BTK inhibitors in Chronic Lymphocytic Leukemia
Leukemia·2025
Tumor Cell Survival Factors and Angiogenesis in Chronic Lymphocytic Leukemia: How Hot Is the Link?
Cancers·2024· 1 citedOpen Access
Epigenetic features support the diagnosis of B-cell prolymphocytic leukemia and identify 2 clinicobiological subtypes
Blood Advances·2024· 3 citedOpen Access
CD38/NAD+ glycohydrolase and associated antigens in chronic lymphocytic leukaemia: From interconnected signalling pathways to therapeutic strategies
Biochimie·2024· 1 cited
Prognostic impact of genetic abnormalities in 536 first‐line chronic lymphocytic leukaemia patients without 17p deletion treated with chemoimmunotherapy in two prospective trials: Focus on IGHV‐mutated subgroups (a <scp>FILO</scp> study)
British Journal of Haematology·2024· 4 citedOpen Access
ACOX1-mediated peroxisomal fatty acid oxidation contributes to metabolic reprogramming and survival in chronic lymphocytic leukemia
Leukemia·2023· 20 citedOpen Access
<i>TRAF3</i>-Inactivated Chronic Lymphocytic Leukemia Cells Show an Enhanced Metabolic Plasticity That Can be Attenuated By Glutaminolysis and Mitochondrial Pyruvate Import Inhibition
Blood·2023· 1 cited
del(8p) and TNFRSF10B loss are associated with a poor prognosis and resistance to fludarabine in chronic lymphocytic leukemia
Leukemia·2023· 4 citedOpen Access
The Value of Neutrophil Gelatinase-Associated Lipocalin Receptor as a Novel Partner of CD38 in Chronic Lymphocytic Leukemia: From an Adverse Prognostic Factor to a Potential Pharmacological Target?
Biomedicines·2023· 3 citedOpen Access
P600: DNA METHYLATION ANALYSIS OF B-CELL PROLYMPHOCYTIC LEUKEMIA REVEALS TWO EPIGENETIC SUBTYPES WITH DISTINCT BIOLOGICAL AND CLINICAL FEATURES
HemaSphere·2023· 1 citedOpen Access
P596: DELETION OF THE SHORT ARM OF CHROMOSOME 8 AND TNFRSF10B LOSS ASSOCIATE TO POOR PROGNOSIS AND DRUG RESISTANCE IN CHRONIC LYMPHOCYTIC LEUKEMIA
HemaSphere·2023Open Access
Extracellular Vesicles in Chronic Lymphocytic Leukemia: Tumor Microenvironment Messengers as a Basis for New Targeted Therapies?
Cancers·2023· 13 citedOpen Access
Current Status of Novel Agents for the Treatment of B Cell Malignancies: What’s Coming Next?
Cancers·2022· 11 citedOpen Access
<i>TRAF3</i> Alterations Identify a Subgroup of Patients with Adverse Clinical Outcome and Induce Metabolic Reprogramming in Chronic Lymphocytic Leukemia
Blood·2022
Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network
Biomolecules·2022· 3 citedOpen Access
Cytogenetic and molecular abnormalities in <scp>W</scp>aldenström's macroglobulinemia patients: Correlations and prognostic impact
American Journal of Hematology·2021· 46 citedOpen Access
Activation of Interferon Signaling in Chronic Lymphocytic Leukemia Cells Contributes to Apoptosis Resistance via a JAK-Src/STAT3/Mcl-1 Signaling Pathway
Biomedicines·2021· 16 citedOpen Access
The antiangiogenic phloroglucinol hyperforin inhibits the secretion of proMMP-2, proMMP-9 and VEGF-A during apoptosis of primary acute myeloid leukemia cells
Journal of Cancer Metastasis and Treatment·2021· 2 citedOpen Access
Clinical and biological features of B‐cell neoplasms with <i>CDK6</i> translocations: an association with a subgroup of splenic marginal zone lymphomas displaying frequent CD5 expression, prolymphocytic cells, and <i>TP53</i> abnormalities
British Journal of Haematology·2020· 14 citedOpen Access
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Frequent Co-authors

Guido Kroemer(46), Naoufal Zamzami(31), Tamara Hirsch(15), Isabel Marzo(12), Philippe Marchetti(12), Josef Penninger(10), Maria Castedo(9), Éric Daugas(9), Nathanaël Larochette(8), L Ravagnan(8), Paola Costantini(7), Didier Decaudin(7), Antonio Macho(7), Catherine Brenner(7), John C. Reed(6), Hans Kristian Lorenzo(5), Karine F. Ferri(5), Zhihua Xie(5), Bruno Dallaporta(5), Naoufal Zamzami(5)