Gerald W. Zamponi

University of Calgary — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

89h-index25.4kcitations645works4.32yr avg
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Research Topics

Ion channel regulation and function(307), Neuroscience and Neuropharmacology Research(176), Pain Mechanisms and Treatments(107), Cardiac electrophysiology and arrhythmias(100), Nicotinic Acetylcholine Receptors Study(73)

Publications642 total

L-type channel voltage-dependent facilitation results from asymmetric π-H and π-π quadrangle interactions at DI–DII domains
2026Open Access
Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents
Neuron·2026
Locus coeruleus microcircuitry processes periaqueductal gray inputs into distinct outputs for regulation of pain and anxiety
Cell Reports·2025Open Access
N-terminal α-amino SUMOylation promotes phosphorylation-independent cofilin-1 translocation to the mitochondrial matrix and induces apoptosis
Nature Communications·2025Open Access
Pharmacological inhibition of NaV1.8 by suzetrigine reveals potent analgesic potential without tolerance development in mice
Molecular Brain·2025Open Access
Cav3.2 channels modulate allodynia but TRP channels are the primary mediators in prenatal valproic acid-induced sensory dysfunction
Neuroscience·2025
A QUÍMICA ANALÍTICA COMO PILAR NA FORMAÇÃO DE ENGENHEIROS: ABORDAGENS DIDÁTICAS E TÉCNICAS FUNDAMENTAIS PARA A PRÁTICA PROFISSIONAL
2025
Phlorotannins from edible marine seaweed Ecklonia stolonifera disrupt USP5-Cav3.2 calcium channel interactions and reverse chronic inflammatory pain
Toxicology and Applied Pharmacology·2025
A pathological missense mutation in the deubiquitinase USP5 leads to insensitivity to pain
The Journal of Experimental Medicine·2025· 5 citedOpen Access
Exploring the role of Cav3.2 calcium channels in autism-like cognitive behavior induced by prenatal valproic acid exposure
Neuroscience·2025· 3 cited
Cav3.1 T‐Type Calcium Channel Acts as a Gateway for <scp>GABAergic</scp> Excitation in the Medial Prefrontal Cortex That Leads to Chronic Psychological Stress Responses in Mice
Acta Physiologica·2025· 3 cited
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels
Molecular Brain·2025Open Access
Biginelli dihydropyrimidines and their acetylated derivatives as L‐/T‐type calcium channel blockers: Synthesis, enantioseparation, and molecular modeling studies
Archiv der Pharmazie·2025· 3 citedOpen Access
The N-type calcium channel rises from the ashes
Journal of Clinical Investigation·2025· 3 citedOpen Access
Divergent sex-specific pannexin-1 mechanisms in microglia and T cells underlie neuropathic pain
Neuron·2025· 29 cited
Entourage effects of nonpsychotropic cannabinoids on visceral sensitivity in experimental colitis
Journal of Pharmacology and Experimental Therapeutics·2025· 3 cited
Synthesis, molecular modeling, DFT studies, and enantioseparation of tetrahydro-4H-chromene derivatives with calcium channel blocking activity
Journal of Molecular Structure·2025· 4 cited
Ca2+ signaling in vascular smooth muscle and endothelial cells in blood vessel remodeling: a review
Inflammation and Regeneration·2024· 9 citedOpen Access
CaV3.2 T-type calcium channels contribute to CGRP- induced allodynia in a rodent model of experimental migraine
The Journal of Headache and Pain·2024· 7 citedOpen Access
Review for "An Open‐Source Tool for Investigation of Differential RNA Expression Between Spinal Cord Cells of Male and Female Mice"
2024
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Frequent Co-authors

Christophe Altier(13), Emmanuel Bourinet(11), John E. McRory(8), Jawed Hamid(8), Terry P. Snutch(6), Lina Chen(6), Joël Nargeot(5), Nathalie Vergnolle(5), Houman Khosravani(5), Terrance P. Snutch(5), Aaron M. Beedle(5), Peter K. Stys(4), Nicolas Cénac(4), Brett Simms(3), Renata Rehak(3), Tuck Wah Soong(3), Vinícius M. Gadotti(3), Ivana A. Souza(3), Patrick L. Stemkowski(3), Ray W. Turner(3)