Michael Tighe

Trudeau Institute — United States

Immunology and Microbiology · Life Sciences

18h-index2.0kcitations34works6.02yr avg
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Research Topics

Immune Cell Function and Interaction(12), T-cell and B-cell Immunology(9), Mosquito-borne diseases and control(9), Viral Infections and Vectors(7), Virology and Viral Diseases(6)

Publications34 total

Mouse Models Uniformly Featuring Human-like Lesions Harboring Drug-tolerant <i>Mycobacterium tuberculosis</i>
2025Open Access
Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19
2024· 3 citedOpen Access
Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets
npj Vaccines·2024· 12 citedOpen Access
Zika purified inactivated virus (ZPIV) vaccine reduced vertical transmission in pregnant immunocompetent mice
npj Vaccines·2024· 9 citedOpen Access
Vaccination by a Zika purified inactivated virus both before and during pregnancy in the common marmoset monkey is associated with relatively normal placental morphology: a preliminary stereological analysis
Placenta·2023
Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets
Research Square (Research Square)·2023Open Access
Zika purified inactivated virus (ZPIV) vaccine efficacy in pregnant human stat2 knock-in mice: neutralizing antibodies as correlates of protection
2023Open Access
Impact of prior dengue virus infection on Zika virus infection during pregnancy in marmosets
Science Translational Medicine·2023· 17 cited
Author Correction: Efficacy of an inactivated Zika vaccine against virus infection during pregnancy in mice and marmosets
npj Vaccines·2022· 3 citedOpen Access
Efficacy of an inactivated Zika vaccine against virus infection during pregnancy in mice and marmosets
npj Vaccines·2022· 22 citedOpen Access
Fibrin Facilitates Both Innate and T Cell-Mediated Defense against Yersinia pestis
UNC Libraries·2020· 1 citedOpen Access
A Novel Human Skin Tissue Model To Study Varicella-Zoster Virus and Human Cytomegalovirus
Journal of Virology·2020· 30 citedOpen Access
Zika virus infection in immunocompetent pregnant mice causes fetal damage and placental pathology in the absence of fetal infection
PLoS Pathogens·2018· 98 citedOpen Access
Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during <i>Mycobacterium tuberculosis</i> infection
The Journal of Experimental Medicine·2015· 72 citedOpen Access
Lymphotoxin beta receptor signaling limits mucosal damage through driving IL-23 production by epithelial cells
Mucosal Immunology·2014· 76 citedOpen Access
Differential and Site Specific Impact of B Cells in the Protective Immune Response to Mycobacterium tuberculosis in the Mouse
PLoS ONE·2013· 54 citedOpen Access
Intranasal Prophylaxis with CpG Oligodeoxynucleotide Can Protect against Yersinia pestis Infection
Infection and Immunity·2013· 15 citedOpen Access
Fibrin Facilitates Both Innate and T Cell–Mediated Defense against <i>Yersinia pestis</i>
The Journal of Immunology·2013· 31 citedOpen Access
Nitric oxide inhibits the accumulation of <scp>CD</scp>4<sup>+</sup><scp>CD</scp>44<sup>hi</sup><scp>T</scp>bet<sup>+</sup><scp>CD</scp>69<sup>lo</sup><scp>T</scp> cells in mycobacterial infection
European Journal of Immunology·2012· 31 citedOpen Access
The aged microenvironment contributes to the age‐related functional defects of CD4 T cells in mice
Aging Cell·2012· 106 citedOpen Access
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Frequent Co-authors

Frank M. Szaba(12), Paula A. Lanthier(11), Kelsey L. Travis(10), Kathleen G. Lanzer(9), In-Jeong Kim(9), Marcia A. Blackman(9), Derek T. Bernacki(8), Stephen J. Thomas(7), Madeline J. Clark(7), Kayvon Modjarrad(7), Timothy C. Low-Beer(6), Tres Cookenham(6), Suzette D. Tardif(6), Jean L. Patterson(6), Andrea M. Cooper(5), Lawrence W. Kummer(5), Debra K. Duso(5), Corinna N. Ross(5), Donna Layne‐Colon(5), Allen G. Harmsen(4)