Ankur K. Nagaraja

Novartis (Switzerland) — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index2.8kcitations46works0.52yr avg
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Research Topics

MicroRNA in disease regulation(19), Circular RNAs in diseases(17), Cancer-related molecular mechanisms research(13), TGF-β signaling in diseases(6), Cancer Genomics and Diagnostics(5)

Publications46 total

925MO First-in-human phase I/Ib study of the oral Werner (WRN) helicase inhibitor HRO761 in patients (pts) with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) advanced solid tumors: Interim safety and efficacy analysis from HRO761 single agent dose escalation
Annals of Oncology·2025· 1 cited
Augmenting Beneficial β2-adrenergic Receptor Signaling and Function Using a Biased Allosteric Modulator
American Journal of Respiratory and Critical Care Medicine·2025
Abstract 2834: CyclinE1 amplification promotes chromosomal instability and distinct vulnerabilities in gastroesophageal adenocarcinoma
Cancer Research·2025· 1 cited
Abstract B019: Cyclin E1 amplification promotes chromosomal instability and distinct vulnerabilities in gastroesophageal adenocarcinoma
Cancer Research·2025
Supplementary Table 4 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 1 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 3 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 2 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table Legends 1-4 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 2 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Data from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 1 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 4 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Data from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table 3 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Supplementary Table Legends 1-4 from Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
2023Open Access
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer
JCO Precision Oncology·2023· 18 citedOpen Access
Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer
Genes & Development·2021· 21 citedOpen Access
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence
Nature Genetics·2021· 103 citedOpen Access
Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma
Gut·2021· 35 citedOpen Access
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Frequent Co-authors

Martin M. Matzuk(28), Preethi H. Gunaratne(21), Chad J. Creighton(18), Matthew L. Anderson(17), Emuejevoke Olokpa(16), Michael D. Fountain(15), Mahjabeen Khan(13), Azam Zariff(13), Adam J. Bass(12), Zhifeng Yu(12), Huifeng Zhu(12), Huifeng Zhu(6), Zhong Wu(6), Jin Zhou(6), James M. McFarland(4), Jeffrey G. Reid(4), Shannon M. Hawkins(4), Mahjabeen Khan(4), Lang Ma(3), Derek Y. Han(3)