Bob Asselbergh

University of Antwerp — Belgium

Neuroscience · Life Sciences

35h-index4.5kcitations67works3.12yr avg
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Research Topics

Hereditary Neurological Disorders(18), Heat shock proteins research(16), Endoplasmic Reticulum Stress and Disease(9), Plant-Microbe Interactions and Immunity(6), Neurogenetic and Muscular Disorders Research(6)

Publications67 total

C9orf72 hexanucleotide repeat expansions impair microglial response in ALS
Nature Neuroscience·2025· 5 citedOpen Access
KCNQ2 Loss-of-Function variants disrupt neuronal maturation via early hyperexcitability followed by maladaptive network remodeling
2025Open Access
Ageing Signatures and Disturbed Muscle Regeneration in Muscle Proteome of Inclusion Body Myositis
Journal of Cachexia Sarcopenia and Muscle·2025· 1 citedOpen Access
Increased TMEM106B levels lead to lysosomal dysfunction which affects synaptic signaling and neuronal health
Molecular Neurodegeneration·2025· 4 citedOpen Access
RNA Interference Targeting Small Heat Shock Protein B8 Failed to Improve Distal Hereditary Motor Neuropathy in the Mouse Model
The Journal of Gene Medicine·2025· 1 cited
Autophagy induction by piplartine ameliorates axonal degeneration caused by mutant HSPB1 and HSPB8 in Charcot-Marie-Tooth type 2 neuropathies
Autophagy·2024· 5 citedOpen Access
An agarose fluidic chip for high-throughput <i>in toto</i> organoid imaging
Lab on a Chip·2024· 3 citedOpen Access
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease
Molecular Neurodegeneration·2024· 6 citedOpen Access
Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling
Nature Communications·2023· 17 citedOpen Access
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies
Autophagy·2023· 25 citedOpen Access
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space
Nature Cell Biology·2023· 72 citedOpen Access
Downregulation of PMP22 ameliorates myelin defects in iPSC-derived human organoid cultures of CMT1A
Brain·2022· 32 citedOpen Access
Heterozygous variants in CTR9, which encodes a major component of the PAF1 complex, are associated with a neurodevelopmental disorder
Genetics in Medicine·2022· 7 cited
Rare missense mutations in ABCA7 might increase Alzheimer’s disease risk by plasma membrane exclusion
Acta Neuropathologica Communications·2022· 22 citedOpen Access
Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction
Brain·2021· 49 citedOpen Access
A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins
The EMBO Journal·2021· 25 citedOpen Access
Contribution of rare homozygous and compound heterozygous VPS13C missense mutations to dementia with Lewy bodies and Parkinson’s disease
Acta Neuropathologica Communications·2021· 41 citedOpen Access
Systematic Quantification of Synapses in Primary Neuronal Culture
iScience·2020· 40 citedOpen Access
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes
Scientific Reports·2020· 46 citedOpen Access
Homozygous and compound heterozygous rare variants in VPS13C contribute to Lewy body diseases
Research Square (Research Square)·2020Open Access
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Frequent Co-authors

Vincent Timmerman(27), Vicky De Winter(14), Riet De Rycke(9), Sophie Janssens(9), Leonardo Almeida‐Souza(8), Albena Jordanova(7), Elias Adriaenssens(7), Joy Irobi(6), Monica Höfte(5), Sofie Goethals(5), Jean‐Pierre Timmermans(5), Ludo Van Den Bosch(5), Biljana Ermanoska(5), Christine Van Broeckhoven(5), Michiel Krols(4), Peter De Jonghe(4), Michaela Auer‐Grumbach(4), Ligia Mateiu(4), Jonathan Baets(4), Eef Parthoens(3)