Kirsten Raun

Novo Nordisk (Denmark) — Denmark

Neuroscience · Life Sciences

34h-index5.1kcitations114works4.52yr avg
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Research Topics

Regulation of Appetite and Obesity(50), Adipose Tissue and Metabolism(26), Diabetes Treatment and Management(19), Neuropeptides and Animal Physiology(17), Biochemical Analysis and Sensing Techniques(17)

Publications112 total

The story of amylin: from physiology to therapy
Nature Metabolism·2026
Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3
Universität Zürich, ZORA·2025Open Access
The effect of amycretin, a unimolecular glucagon-like peptide-1 and amylin receptor agonist, on body weight and metabolic dysfunction in mice and rats
EBioMedicine·2025· 7 citedOpen Access
CagriSema drives weight loss in rats by reducing energy intake and preserving energy expenditure
Nature Metabolism·2025· 5 citedOpen Access
Characterization of 0839 – A tool compound for pre-clinical mode-of-action studies of amylin analogues such as cagrilintide
Life Sciences·2025Open Access
Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3
EBioMedicine·2025· 8 citedOpen Access
86-OR: The Amylin Receptor Selective Agonist NN1213 Reduces Food Intake and Body Weight in Rats without Decreasing Calcium Plasma Levels
Diabetes·2025
1693-P: Cagrisema-Induced Weight Loss in Diet-Induced Obese Rats Relies on Preserved Mitochondrial Leak Respiration in Skeletal Muscle
Diabetes·2025· 1 cited
Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors
Nature Communications·2025· 8 citedOpen Access
A once-daily GLP-1/GIP/glucagon receptor tri-agonist (NN1706) lowers body weight in rodents, monkeys and humans
Molecular Metabolism·2025· 11 citedOpen Access
A single dorsal vagal complex circuit mediates the aversive and anorectic responses to GLP1R agonists
2025· 7 citedOpen Access
A Cross-Species Atlas of the Dorsal Vagal Complex Reveals Neural Mediators of Cagrilintide’s Effects on Energy Balance
2025· 8 citedOpen Access
Cagrilintide Lowers Bodyweight Through Brain Amylin Receptors 1 and 3
SSRN Electronic Journal·2025Open Access
Correction to “NN1213 – A Potent, Long-Acting, and Selective Analog of Human Amylin”
Journal of Medicinal Chemistry·2024· 1 citedOpen Access
Housing mice near vs. below thermoneutrality affects drug-induced weight loss but does not improve prediction of efficacy in humans
Cell Reports·2024· 14 citedOpen Access
NN1213 – A Potent, Long-Acting, and Selective Analog of Human Amylin
Journal of Medicinal Chemistry·2024· 10 citedOpen Access
763-P: CagriSema Improves Insulin Sensitivity in Diet-Induced Obese Rats
Diabetes·2024· 2 cited
Improved leptin sensitivity and increased soluble leptin receptor concentrations may underlie the additive effects of combining PYY(3–36) and exendin-4 on body weight lowering in diet-induced obese mice
Heliyon·2024· 3 citedOpen Access
Improved Leptin Sensitivity and Increased Soluble Leptin Receptor May Underlie the Additive Effects of Combining Pyy(3-36) and Exendin-4 on Body Weight Lowering in Diet-Induced-Obese Mice
SSRN Electronic Journal·2024Open Access
Body weight lowering effect of glucose-dependent insulinotropic polypeptide and glucagon-like peptide receptor agonists is more efficient in RAMP1/3 KO than in WT mice
European Journal of Pharmacology·2023· 9 citedOpen Access
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Frequent Co-authors

Birgitte S. Wulff(9), Valeria Golozoubova(7), Lotte Bjerre Knudsen(6), Jesper Lau(6), Anna Secher(5), Linu M. John(5), Cecilia Nilsson(5), Berit Østergaard Christoffersen(5), Birgitte Andersen(5), Marina Kjærgaard Gerstenberg(5), Henning Thøgersen(5), Kevin L. Grove(4), K. Madsen(4), Carsten E. Stidsen(4), Kilian W. Conde‐Frieboes(4), Michael J. Raschke(4), Hermann Josef Bail(4), Stefan Kolbeck(4), Birgit Sehested Hansen(4), Michael Ankersen(4)