Hubert Schwarz

KTH Royal Institute of Technology — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index371citations34works0.02yr avg
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Research Topics

Viral Infectious Diseases and Gene Expression in Insects(15), Protein purification and stability(12), Monoclonal and Polyclonal Antibodies Research(5), 3D Printing in Biomedical Research(4), Historical Influence and Diplomacy(3)

Publications34 total

A predictive modular approach to constraint satisfaction under uncertainty — with application to glycosylation in continuous monoclonal antibody biosimilar production
Journal of Process Control·2026Open Access
Optimization of medium with perfusion microbioreactors for high density CHO cell cultures at very low renewal rate aided by design of experiments
Biotechnology and Bioengineering·2023· 28 citedOpen Access
Product sieving of <scp>mAb</scp> and its high molecular weight species in different modes of <scp>ATF</scp> and <scp>TFF</scp> perfusion cell cultures
Journal of Chemical Technology & Biotechnology·2023· 10 citedOpen Access
Continuous Bioprocessing for Upstream Process: Perfusion Process
Cell engineering·2023· 3 cited
Integrated continuous biomanufacturing on pilot scale for acid‐sensitive monoclonal antibodies
Biotechnology and Bioengineering·2022· 40 citedOpen Access
Monitoring of amino acids and antibody N-glycosylation in high cell density perfusion culture based on Raman spectroscopy
Biochemical Engineering Journal·2022· 41 citedOpen Access
Design of an integrated continuous downstream process for acid-sensitive monoclonal antibodies based on a calcium-dependent Protein A ligand
Journal of Chromatography A·2022· 23 citedOpen Access
Back Cover Image, Volume 118, Number 9, September 2021
Biotechnology and Bioengineering·2021
Antibody capture process based on magnetic beads from very high cell density suspension
Biotechnology and Bioengineering·2021· 16 citedOpen Access
Control of IgG glycosylation in CHO cell perfusion cultures by GReBA mathematical model supported by a novel targeted feed, TAFE
Metabolic Engineering·2020· 39 citedOpen Access
Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells
iScience·2020· 56 citedOpen Access
Model‐based design and control of a small‐scale integrated continuous end‐to‐end <scp>mAb</scp> platform
Biotechnology Progress·2020· 54 citedOpen Access
Author response for "Model-based design and control of a small-scale integrated continuous end-to-end mAb platform"
2020
Small-scale bioreactor supports high density HEK293 cell perfusion culture for the production of recombinant Erythropoietin
Journal of Biotechnology·2019· 57 cited
Novel amino acid feeding strategy in perfusion cultures to enhance monoclonal antibody production
2019
Small scale end-to-end mAb platform with a continuous, integrated and compact process
2019
Small-scale end-to-end mAb platform with a continuous and integrated design
2019· 2 cited
Strategy for targeted delivery of key nutrients in high cell density perfusion
2019
Production of biopharmaceuticals in an intensified perfusion process of HEK 293 cells
2018
Development and application of screening scale bioreactor systems for very high cell density perfusion of mammalian cells
2017· 1 cited
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Frequent Co-authors

Véronique Chotteau(20), Andreas Castan(7), Niklas Andersson(6), Bernt Nilsson(6), Caijuan Zhan(5), Joaquín Gomis‐Fons(5), Johan Rockberg(4), Anita Solbrand(4), Atefeh Shokri(4), Magdalena Malm(3), Ray Field(3), Richard Turner(3), Christopher Sellick(2), Paul Varley(2), Joanne Stevenson(2), Meeri Mäkinen(2), M. Isaksson(2), Julia Scheffel(2), Sophia Hober(2), Nils A. Brechmann(2)