Manmeet K. Mamik

Immunology and Microbiology · Life Sciences

11h-index1.4kcitations16works0.02yr avg
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Research Topics

HIV Research and Treatment(9), Inflammasome and immune disorders(7), Neuroinflammation and Neurodegeneration Mechanisms(6), interferon and immune responses(5), Immune Response and Inflammation(3)

Publications16 total

Peroxisome Injury in Multiple Sclerosis: Protective Effects of 4-Phenylbutyrate in CNS-Associated Macrophages
Journal of Neuroscience·2022· 35 citedOpen Access
Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
Proceedings of the National Academy of Sciences·2018· 525 citedOpen Access
Live or let die: Pyroptosis and inflammasome activation in glial cells during multiple sclerosis and experimental autoimmune encephalomyelitis
The Journal of Immunology·2018· 1 cited
Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain
Retrovirology·2017· 67 citedOpen Access
Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts
Brain·2017· 167 citedOpen Access
Immune Sensors and Effectors of Health and Disease
2016· 2 cited
Insulin Treatment Prevents Neuroinflammation and Neuronal Injury with Restored Neurobehavioral Function in Models of HIV/AIDS Neurodegeneration
Journal of Neuroscience·2016· 79 citedOpen Access
HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation
Journal of Neuroimmune Pharmacology·2016· 149 cited
CNS Inflammasome Activation and Modulation in Multiple Sclerosis (P5.333)
Neurology·2016
Insulin Signaling Suppresses Virus Replication and Neuroinflammation in HIV/AIDS (S53.005)
Neurology·2016
CXCL8 as a Potential Therapeutic Target for HIV-Associated Neurocognitive Disorders
Current Drug Targets·2015· 22 cited
HIV-1 Vpr activates the NLRP3 inflammasome in primary human microglia
Journal of Neuroimmunology·2014
Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS
Retrovirology·2014· 236 citedOpen Access
Chemokine CXCL8 Promotes HIV-1 Replication in Human Monocyte-Derived Macrophages and Primary Microglia via Nuclear Factor-κB Pathway
PLoS ONE·2014· 29 citedOpen Access
Src Homology-2 Domain-Containing Protein Tyrosine Phosphatase (SHP) 2 and p38 Regulate the Expression of Chemokine CXCL8 in Human Astrocytes
PLoS ONE·2012· 33 citedOpen Access
HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms
Journal of Neuroinflammation·2011· 42 citedOpen Access

Frequent Co-authors

Christopher Power(12), Brienne McKenzie(9), William G. Branton(9), Anuja Ghorpade(4), Leina B. Saito(3), Éric A. Cohen(3), Eugene L. Asahchop(3), Roobina Boghozian(2), Maria Chiara Monaco(2), Jian‐Qiang Lu(2), Jesse Chisholm(2), Wing Fuk Chan(2), Yu Zhu(2), Eugene O. Major(1), J. Walsh(1), Stacey N. Reinke(1), Ferdinand Maingat(1), David Broadhurst(1), Elizabeth Hui(1), Oussama Méziane(1)