Benjamin J. Doranz

Integral Molecular (United States) — United States

Medicine · Health Sciences

62h-index16.9kcitations209works1.12yr avg
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Research Topics

Mosquito-borne diseases and control(54), Monoclonal and Polyclonal Antibodies Research(52), Viral Infections and Vectors(45), HIV Research and Treatment(39), Immune Cell Function and Interaction(31)

Publications209 total

8 Pan-reactive mAbs enable preclinical animal models: high-quality mAb reagents for hitting targets in diverse animal species
Regular and Young Investigator Award Abstracts·2025Open Access
29 A new approach methodology (NAM) for specificity testing: ISTAND qualification of the Membrane Proteome Array to evaluate off-target binding of MAb-based therapies
Regular and Young Investigator Award Abstracts·2025Open Access
991 Up to one-third of antibody drugs are nonspecific: a systematic evaluation of drugs throughout clinical and preclinical development
Regular and Young Investigator Award Abstracts·2025Open Access
981 GPRC5D multispecific antibodies targeting multiple myeloma
Regular and Young Investigator Award Abstracts·2025Open Access
391 Developing a comprehensive proteome array assessing MAb specificity: testing binding interactions against >7,000 native membrane and secreted proteins
Regular and Young Investigator Award Abstracts·2025Open Access
Identification of the seven critical residues that control ZIKV-DENV cross-reactivity to engineer a non-cross-reactive ZIKV vaccine
Cell Reports·2025Open Access
Abstract 3406: GPRC5D multispecific antibodies with potent anti-tumor activity against multiple myeloma
Cancer Research·2025· 1 cited
Abstract 1161: A systematic evaluation of off-target binding in antibody-based biologics during clinical and preclinical development
Cancer Research·2025
Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane
Nature Communications·2025· 3 citedOpen Access
Redefining antibody patent protection using paratope mapping and CDR-scanning
Nature Biotechnology·2025· 2 cited
1084 A systematic evaluation of off-target binding in antibody-based molecules during clinical and preclinical development
Regular and Young Investigator Award Abstracts·2024Open Access
1030 Identifying new cellular adjuvants for cancer vaccines and immunotherapies
Regular and Young Investigator Award Abstracts·2024Open Access
1075 Bispecific and trispecific GPRC5D antibodies with potent cell-killing activity against multiple myeloma
Regular and Young Investigator Award Abstracts·2024Open Access
469 Specificity testing of antibodies, multispecifics, and CAR-T therapeutics for IND using the membrane proteome array
Regular and Young Investigator Award Abstracts·2024Open Access
A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variants
Antibody Therapeutics·2024· 1 citedOpen Access
Abstract 718: CCR8 antibody drug conjugates: Targeting regulatory T cells for tumor sensitization
Cancer Research·2024
Abstract 2374: Bispecific and trispecific GPRC5D antibodies with potent cell-killing activity against multiple myeloma
Cancer Research·2024
Abstract 6743: Identifying new cellular adjuvants for cancer vaccines and immunotherapies
Cancer Research·2024
Abstract 5798: Preclinical safety assessment for specificity of biotherapeutics using the membrane proteome array
Cancer Research·2024
Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques
Nature Communications·2024· 14 citedOpen Access
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Frequent Co-authors

Robert W. Doms(20), Edgar Davidson(16), Joseph Rucker(14), James E. Crowe(14), Marc Parmentier(12), Rachel H. Fong(8), Michael Diamond(8), Hannah L. Turner(8), Andrew B. Ward(8), Gilbert Vassart(7), Nurgun Kose(7), Benhur Lee(7), Matthew Sharron(7), Michel Samson(6), Cédric Blanpain(6), Erica Ollmann Saphire(6), Kristen M. Kahle(6), Andrew I. Flyak(6), Ronald G. Collman(5), Julie M. Fox(5)