Akie Maehara

Juntendo University — Japan

Immunology and Microbiology · Life Sciences

17h-index1.1kcitations39works2.32yr avg
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Research Topics

Mast cells and histamine(11), Asthma and respiratory diseases(9), Immune Response and Inflammation(9), Food Allergy and Anaphylaxis Research(9), Immune Cell Function and Interaction(9)

Publications39 total

IgE- and Mast Cell-Dependent Anaphylaxis is Regulated by Sphingolipid Binding to Activating and Inhibitory CD300 Family Members
Journal of Allergy and Clinical Immunology·2026
Fabs targeting a Cε2 epitope disassemble IgE-receptor complexes and suppress anaphylaxis
Journal of Allergy and Clinical Immunology·2025
Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability
Frontiers in Immunology·2024· 10 citedOpen Access
Intranasal administration of ceramide liposome suppresses allergic rhinitis by targeting CD300f in murine models
Scientific Reports·2024· 4 citedOpen Access
Identification of IgE cross-reactive allergens causing food allergies including pollen-food allergy syndrome (PFAS)
Journal of Allergy and Clinical Immunology·2024Open Access
Identification of IgE Cross-reactive Allergens Causing Food Allergies Using Murine Models
Juntendo Medical Journal·2024Open Access
Murine model identifies tropomyosin as IgE cross-reactive protein between house dust mite and coho salmon that possibly contributes to the development of salmon allergy
Frontiers in Immunology·2023· 7 citedOpen Access
Staphylococcus aureus δ-toxin present on skin promotes the development of food allergy in a murine model
Frontiers in Immunology·2023· 22 citedOpen Access
Development of mouse model for oral allergy syndrome to identify IgE cross-reactive pollen and food allergens: ragweed pollen cross-reacts with fennel and black pepper
Frontiers in Immunology·2022· 7 citedOpen Access
The development of biologics inhibiting IL-33signaling on the basis of the signal transduction mechanisms
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2022Open Access
A Possible Association Between a Nucleotide‐Binding Domain LRR‐Containing Protein Family PYD‐Containing Protein 1 Mutation and an Autoinflammatory Disease Involving Liver Cirrhosis
Hepatology·2021· 11 cited
CD300f is a potential therapeutic target for the treatment of food allergy
Allergy·2019· 27 cited
Differential Lipid Recognition by Mouse versus Human CD300f, Inhibiting Passive Cutaneous Anaphylaxis, Depends on a Single Amino Acid Substitution in its Immunoglobulin-Like Domain
Journal of Investigative Dermatology·2019· 11 citedOpen Access
Ceramide-CD300f interaction inhibits Mrgprb2-mediated mast cell activation and pseudo-allergic drug reactions in mice
The Journal of Immunology·2019· 1 cited
The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide–dependent neutrophil recruitment
Science Signaling·2019· 18 cited
Differential lipid recognition by mouse versus human CD300f, inhibiting IgE-mediated mast cell activation, depends on a single amino acid substitution in its immunoglobulin-like domain
日本免疫学会総会・学術集会記録(CD-ROM)·2019
Mast cell- and IgE-dependent anaphylaxis is regulated by the interaction between inhibitory LMIR3/activating LMIR7 and specific lipids
日本免疫学会総会・学術集会記録(CD-ROM)·2019
An inhibitory receptor CD300f inhibits the pathogenesis of OVA-induced food allergy in mice
日本免疫学会総会・学術集会記録(CD-ROM)·2019
Identification of inhibitory mechanisms in pseudo-allergy involving Mrgprb2/MRGPRX2-mediated mast cell activation
Journal of Allergy and Clinical Immunology·2018· 31 cited
Leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 is an FcRγ-coupled receptor selectively expressed in mouse tissue plasmacytoid dendritic cells
Scientific Reports·2018· 7 citedOpen Access
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Frequent Co-authors

Jiro Kitaura(38), Ayako Kaitani(32), Kumi Izawa(27), Nobuhiro Nakano(22), Toshio Kitamura(20), Ko Okumura(20), Tomoaki Ando(18), Hideoki Ogawa(16), Masamichi Isobe(15), Toshihiko Oki(14), Toshiaki Shimizu(14), Shino Uchida(14), Mariko Takahashi(12), Keiko Maeda(12), Yoshinori Yamanishi(11), Koichiro Uchida(11), Risa Yamamoto(10), Masakazu Nagamine(9), Hiromichi Yamada(9), Hexing Wang(9)