Rick Cote

University of New Hampshire — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index10.4kcitations195works3.22yr avg
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Research Topics

Phosphodiesterase function and regulation(47), Retinal Development and Disorders(41), Cholinesterase and Neurodegenerative Diseases(20), Receptor Mechanisms and Signaling(18), Photoreceptor and optogenetics research(17)

Publications194 total

Digital Modeling of Spatial Pathway Activity from Histology Reveals Tumor Microenvironment Heterogeneity
arXiv (Cornell University)·2025Open Access
Roles of Cyclic Nucleotide Phosphodiesterases in Signal Transduction Pathways in the Nematode Caenorhabditis elegans
Cells·2025Open Access
Cyclic nucleotide phosphodiesterases as drug targets
Pharmacological Reviews·2025· 16 citedOpen Access
60. AI-guided histopathology predicts brain metastasis in lung cancer patients
Cancer Genetics·2024
1. Enrichment of Hodgkin and Reed-Sternberg (HRS) cells using size-based microfiltration
Cancer Genetics·2024Open Access
85. Microfilter enrichment of Hodgkin and Reed-Sternberg (HRS) cells
Cancer Genetics·2023
Radical Cystectomy in the Treatment of Invasive Bladder Cancer: Long-Term Results in 1,054 Patients
Journal of Clinical Oncology·2023· 257 cited
Coupling of conformational dynamics and inhibitor binding in the phosphodiesterase‐5 family
Protein Science·2023· 4 citedOpen Access
Automatic Detection of Circulating Tumor Cells and Cancer Associated Fibroblasts using Deep Learning
Research Square (Research Square)·2022· 1 citedOpen Access
Urothelial Cancer
Holland‐Frei Cancer Medicine·2022
All-in-focus fine needle aspiration biopsy imaging based on Fourier ptychographic microscopy
Journal of Pathology Informatics·2022· 22 citedOpen Access
Photoreceptor phosphodiesterase (PDE6): activation and inactivation mechanisms during visual transduction in rods and cones
Pflügers Archiv - European Journal of Physiology·2021· 31 citedOpen Access
Photoreceptor phosphodiesterase (PDE6): structure, regulatory mechanisms, and implications for treatment of retinal diseases
2021· 1 cited
Photoreceptor Phosphodiesterase (PDE6): Structure, Regulatory Mechanisms, and Implications for Treatment of Retinal Diseases
Advances in experimental medicine and biology·2021· 27 citedOpen Access
Immunohistochemical expression of receptors for luteinizing hormone-releasing hormone (LHRHR) in muscle-invasive Urothelial carcinoma of urinary bladder: a potential predictive marker for targeted cytotoxic LHRH hybrid analogs
Surgical and Experimental Pathology·2020Open Access
Structural Analysis of the Regulatory GAF Domains of cGMP Phosphodiesterase Elucidates the Allosteric Communication Pathway
Journal of Molecular Biology·2020· 13 citedOpen Access
Abstract B65: Precompetitive collaboration on liquid biopsy for early cancer assessment
Clinical Cancer Research·2020
Contrasting Circulating Tumor Cells and Free Circulating DNA Responses in Men Treated for Prostate Cancer after Primary Versus Salvage Radiotherapy
Clinical Oncology and Research·2020· 1 citedOpen Access
The molecular architecture of photoreceptor phosphodiesterase 6 (PDE6) with activated G protein elucidates the mechanism of visual excitation
Journal of Biological Chemistry·2019· 19 citedOpen Access
Allosteric Regulation of Rod Photoreceptor Phosphodiesterase 6 (PDE6) Elucidated by Chemical Cross-Linking and Quantitative Mass Spectrometry
Journal of Molecular Biology·2019· 14 citedOpen Access
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Frequent Co-authors

Ram H. Datar(8), Arun Majumdar(3), Debra Hawes(3), M D Bownds(3), Anthony Williams(3), Siddarth Rawal(3), John P. Stein(2), Gary Lieskovsky(2), Susan Groshen(2), An‐Chen Feng(2), Stuart D. Boyd(2), Eila C. Skinner(2), Bernard H. Bochner(2), Duriayai Thangathurai(2), Maged Mikhail(2), Derek Raghavan(2), Guanghua Wu(2), Hai‐Feng Ji(2), Karolyn M. Hansen(2), Thomas Thundat(2)