Jenny Hetzer

German Cancer Research Center — Germany

Medicine · Health Sciences

7h-index468citations22works9.12yr avg
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Research Topics

Liver Disease Diagnosis and Treatment(6), MicroRNA in disease regulation(3), Single-cell and spatial transcriptomics(3), Phagocytosis and Immune Regulation(3), Gut microbiota and health(2)

Publications22 total

Activated ATF6α is a hepatic tumour driver restricting immunosurveillance
Nature·2026Open Access
Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease
Free Radical Biology and Medicine·2025
Targeting peroxiredoxin 2 prevents hepatocarcinogenesis in metabolic liver disease models
Journal of Clinical Investigation·2025· 1 citedOpen Access
Bifidobacteria-derived exopolysaccharide promotes anti-tumor immunity
Cell Reports·2025· 4 citedOpen Access
Non-antibiotics disrupt colonization resistance against enteropathogens
Nature·2025· 20 citedOpen Access
FRI-064 MicroRNA-122 functions as a rheostat regulating liver tolerance, inflammation and fibrosis
Journal of Hepatology·2025
Abstract 2369: Targeting peroxiredoxin 2 prevents hepatocellular carcinoma development in metabolic liver disease
Cancer Research·2025
Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis
Zeitschrift für Gastroenterologie·2025
Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis
2024Open Access
OS-103 Antibiotic-mediated microbiota depletion limits IgA-related fibrogenesis in metabolic dysfunction-associated steatohepatitis
Journal of Hepatology·2024
A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
Cell Metabolism·2024· 75 citedOpen Access
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice
Developmental Cell·2023· 39 citedOpen Access
Beneficial effects of intermittent fasting in NASH and subsequent HCC development are executed by concerted PPARα and PCK1 action in hepatocytes
2023· 2 citedOpen Access
Spatially Resolved Multi-Omics Single-Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer
Gastroenterology·2023· 84 citedOpen Access
Peroxiredoxin 2 is a target for hepatocellular carcinoma chemoprevention
Journal of Hepatology·2022
Epithelial cells of the intestine acquire cell-intrinsic inflammation signatures during ageing
2021· 2 citedOpen Access
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery
Nature Communications·2021· 40 citedOpen Access
Publisher Correction: Inhibition of LTβR signalling activates WNT-induced regeneration in lung
Nature·2020· 7 citedOpen Access
Inhibition of LTβR signalling activates WNT-induced regeneration in lung
Nature·2020· 165 citedOpen Access
A human liver cell-based system modeling a clinical prognostic liver signature combined with single cell RNA-seq for discovery of novel liver disease therapeutics
Journal of Hepatology·2020Open Access
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Frequent Co-authors

Mathias Heikenwälder(20), Danijela Heide(18), Émilie Crouchet(7), Naoto Fujiwara(7), Hussein El Saghire(7), Frank Jühling(7), Clara Ponsolles(7), Marine A. Oudot(7), Sarah Durand(7), Emanuele Felli(7), Patrick Pessaux(7), Catherine Schuster(7), Nathalie Pochet(7), Yujin Hoshida(7), Thomas F. Baumert(7), Sandra Prokosch(6), Ulrike Rothermel(5), Christoph Trautwein(5), Maja C. Funk(4), Michael Boutros(4)