Mette Villingshøj

Copenhagen University Hospital — Denmark

Medicine · Health Sciences

11h-index505citations23works0.02yr avg
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Research Topics

Glioma Diagnosis and Treatment(14), HER2/EGFR in Cancer Research(5), Cancer Cells and Metastasis(4), Histone Deacetylase Inhibitors Research(4), Cancer Treatment and Pharmacology(4)

Publications23 total

VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance
Neuro-Oncology·2018· 86 citedOpen Access
Targeting glioma stem‐like cell survival and chemoresistance through inhibition of lysine‐specific histone demethylase <scp>KDM</scp>2B
Molecular Oncology·2018· 73 citedOpen Access
ACTR-26. TOXICITY AND EFFICACY OF LOMUSTINE PLUS BEVACIZUMAB IN RECURRENT GLIOBLASTOMA PATIENTS
Neuro-Oncology·2017Open Access
DRES-01. ROLE OF HISTONE LYSINE DEMETHYLASE KDM2B IN GLIOBLASTOMA TUMOR CELL MAINTENANCE AND CHEMORESISTANCE
Neuro-Oncology·2017Open Access
Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine
Cellular Oncology·2016· 61 cited
Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro
Cancer Cell International·2016· 12 citedOpen Access
ANGI-15COMBINED TARGETING OF NOTCH AND EGFR DISPLAY ADDITIVE INHIBITORY EFFECTS ON ANGIOGENESIS AND SURVIVAL IN GLIOBLASTOMA
Neuro-Oncology·2015Open Access
ANGI-11VEGF-C CONTRIBUTES TO AUTOCRINE VEGFR2 SIGNALING AND AFFECTS CELL VIABILITY AND TUMOR GROWTH IN GLIOBLASTOMA
Neuro-Oncology·2015Open Access
Abstract 1369: Inhibition of Notch- and EGFR signaling reduces cell viability and angiogenesis in glioblastoma multiforme
Cancer Research·2015· 1 cited
P01.18 * AUTOCRINE VEGFC-VEGFR2 SIGNALING IS OF IMPORTANCE FOR THE GROWTH OF GLIOBLASTOMA MULTIFORME
Neuro-Oncology·2014Open Access
P01.20 * EPIGENETIC TREATMENT AND INDUCTION OF DIFFERENTIATION IN GLIOBLASTOMA MULTIFORME NEUROSPHERE CELLS LEADS TO DOWNREGULATION OF EGFR, EGFRVIII AND NESTIN TOGETHER WITH REDUCED COLONY FORMATION IN VITRO
Neuro-Oncology·2014· 1 citedOpen Access
Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature
Cancer Biology & Therapy·2014· 10 citedOpen Access
Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures
Cancer Biology & Therapy·2013· 42 citedOpen Access
Abstract 3339: The role of active Notch signaling in glioblastoma neurosphere cultures
Cancer Research·2012
Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme
Experimental Cell Research·2011· 50 cited
Improved Response by Co-targeting EGFR/EGFRvIII and Src Family Kinases in Human Cancer Cells
Cancer Investigation·2009· 13 cited
36The function of normal and mutated epidermal growth factor receptors in Glioblastoma Multiforme 
- Establishment of an<i>in vivo</i>and<i>in vitro</i>model
Apmis·2008
36 The function of normal and mutated epidermal growth factor receptors in Glioblastoma Multiforme – Establishment of an in vivo and in vitro model
Apmis·2008
EGFR induces expression of IRF‐1 <i>via</i> STAT1 and STAT3 activation leading to growth arrest of human cancer cells
International Journal of Cancer·2007· 47 cited
The function of normal and mutated epidermal growth facor receptors in glioblastoma multiforme: Establishment of an in vivo and in vitro model
Cancer Research·2007
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Frequent Co-authors

Hans Skovgaard Poulsen(21), Marie‐Thérése Stockhausen(12), Signe Regner Michaelsen(9), Mikkel Staberg(8), Helle Broholm(7), Petra Hamerlik(7), Mette Kjølhede Nedergaard(6), Mogens Spang‐Thomsen(5), Karina Kristoffersen(4), Michael Kosteljanetz(4), Henriette Pedersen(3), Andreas Kjær(3), Rikke Rasmussen(3), Louise Stobbe Olsen(3), Kamilla E. Jensen(2), Thomas Urup(2), Jane Skjøth‐Rasmussen(2), Jannick Brennum(2), Ulrik Lassen(2), Mikkel W. Pedersen(2)