Farhana Pruthi

Amicus Therapeutics (United States) — United States

Neuroscience · Life Sciences

7h-index500citations8works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(5), Ion channel regulation and function(4), Receptor Mechanisms and Signaling(4), Neurotransmitter Receptor Influence on Behavior(2), Cardiac electrophysiology and arrhythmias(2)

Publications8 total

The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat
Genetics in Medicine·2016· 207 citedOpen Access
Strategy to assess the effect of duvoglustat co-administered with alglucosidase alfa infusion on the immune response to enzyme replacement therapy for Pompe disease
Molecular Genetics and Metabolism·2014
WS-50030 [7-{4-[3-(1H-inden-3-yl)propyl]piperazin-1-yl}-1,3-benzoxazol-2(3H)-one]: A Novel Dopamine D2 Receptor Partial Agonist/Serotonin Reuptake Inhibitor with Preclinical Antipsychotic-Like and Antidepressant-Like Activity
Journal of Pharmacology and Experimental Therapeutics·2009· 14 cited
Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia
Bioorganic & Medicinal Chemistry Letters·2009· 18 citedOpen Access
ADX47273 [S-(4-Fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: A Novel Metabotropic Glutamate Receptor 5-Selective Positive Allosteric Modulator with Preclinical Antipsychotic-Like and Procognitive Activities
Journal of Pharmacology and Experimental Therapeutics·2008· 181 cited
Pharmacological characterization of recombinant N-type calcium channel (Cav2.2) mediated calcium mobilization using FLIPR
Biochemical Pharmacology·2006· 29 cited
State-Dependent Compound Inhibition of Nav1.2 Sodium Channels Using the FLIPR Vm Dye: On-Target and Off-Target Effects of Diverse Pharmacological Agents
SLAS DISCOVERY·2006· 36 citedOpen Access
Validation of a Fluorescent Imaging Plate Reader Membrane Potential Assay for High-Throughput Screening of Glycine Transporter Modulators
SLAS DISCOVERY·2005· 15 citedOpen Access

Frequent Co-authors

Kenneth J. Valenzano(5), Elfrida R. Benjamin(4), Rachel L. Navarra(3), Radka Graf(3), Margaret Lai(3), Mark H. Pausch(3), Karen L. Marquis(3), Shakira Olanrewaju(3), Victor I. Ilyin(3), Maria Cecilia Della Valle(2), Xiaoyang Wu(2), Evan Katz(2), Carrolee Barlow(2), David J. Lockhart(2), Caitlin Wantuch(2), Deborah L. Smith(2), Claudine Pulicicchio(2), Chad E. Beyer(2), Sharon Rosenzweig‐Lipson(2), Richard M. Woodward(2)