Istvan Botos

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index4.4kcitations101works1.52yr avg
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Research Topics

Bacterial Genetics and Biotechnology(25), RNA and protein synthesis mechanisms(19), Enzyme Structure and Function(15), Enzyme Production and Characterization(10), Immune Response and Inflammation(9)

Publications101 total

Structure-based design of an opioid receptor modulator for enhanced morphine analgesia
UNC Libraries·2026Open Access
Structure-based design of an opioid receptor modulator for enhanced morphine analgesia
Science Advances·2026Open Access
Orchestrating NTSR1 signaling from the interface
UNC Libraries·2026Open Access
The dynamic lateral gate of the mitochondrial β-barrel biogenesis machinery is blocked by darobactin A
Nature Communications·2025Open Access
Structural insights into Cir-mediated killing by the antimicrobial protein Microcin V
Communications Biology·2025· 1 citedOpen Access
Cryo-EM structures of the E. coli Ton and Tol motor complexes
Nature Communications·2025· 5 citedOpen Access
Structural Insights into Cir-mediated Killing by the Antimicrobial Protein Microcin V
2025Open Access
Olfactomedin 4 promotes gastric cancer cell G2/M progression and serves as a therapeutic target in gastric adenocarcinoma
Carcinogenesis·2025· 1 cited
Cryo-EM structures of the <i>E. coli</i> Ton and Tol motor complexes
2024· 4 citedOpen Access
The Name Is Barrel, β-Barrel
Methods in molecular biology·2024· 4 cited
Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids
JACS Au·2023· 8 citedOpen Access
OLFM4-RET fusion is an oncogenic driver in small intestine adenocarcinoma
Oncogene·2021· 11 cited
Building Better Barrels – β-barrel Biogenesis and Insertion in Bacteria and Mitochondria
Journal of Molecular Biology·2021· 43 citedOpen Access
Towards Mechanistic Understanding of Mitochondrial β-Barrel Biogenesis: Structural Studies of the Sorting and Assembly Machinery
Biophysical Journal·2021Open Access
Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA
Nucleic Acids Research·2020· 31 citedOpen Access
Cyclopentane peptide nucleic acid in complex with DNA
2020
Author Correction: Cryo-EM structure of the bacterial Ton motor subcomplex ExbB–ExbD provides information on structure and stoichiometry
Communications Biology·2020Open Access
Structural insight into toxin secretion by contact-dependent growth inhibition transporters
eLife·2020· 25 citedOpen Access
Author response: Structural insight into toxin secretion by contact-dependent growth inhibition transporters
2020· 1 citedOpen Access
Structural insight into mitochondrial β-barrel outer membrane protein biogenesis
Nature Communications·2020· 82 citedOpen Access
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Frequent Co-authors

Alexander Wlodawer(21), Susan K. Buchanan(12), Т. В. Ротанова(10), Alla Gustchina(9), Edward E. Melnikov(8), David R. Davies(7), David M. Segal(6), O.V. Makhovskaya(5), Joseph Shiloach(4), Scott Cherry(4), Joseph E. Tropea(4), Hervé Celia(4), Roland Lloubès(4), Barry R. O’Keefe(4), Erik Meyer(4), А. Г. Андрианова(4), Jessica K. Bell(3), Pamela R. Hall(3), Janine Askins(3), Anna G. Khalatova(3)