Meagan B. Ryan

Princess Margaret Cancer Centre — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index2.4kcitations136works1.22yr avg
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Research Topics

Melanoma and MAPK Pathways(82), PARP inhibition in cancer therapy(28), Lung Cancer Treatments and Mutations(21), NF-κB Signaling Pathways(20), Protein Kinase Regulation and GTPase Signaling(18)

Publications136 total

Assessing the feasibility and external validity of natural language processing-extracted data for advanced lung cancer patients
Lung Cancer·2025· 3 citedOpen Access
Cell type–specific epigenetic priming of gene expression in nucleus accumbens by cocaine
Science Advances·2024· 18 citedOpen Access
519LBA (PB-519) LBA Posters: The novel pan-RAF-MEK glue NST-628 is highly efficacious as monotherapy and as an anchor for vertical inhibition of the RAS-MAPK pathway in KRAS-mutant cancers
European Journal of Cancer·2024
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
UNC Libraries·2024Open Access
Supplementary Table 1 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Methods from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 6 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Figures S1-S12 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 8 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 7 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Methods from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 8 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 10 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Tables 2-5 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 10 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 9 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 6 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Data from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Table 9 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
Supplementary Tables 2-5 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
2024Open Access
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Frequent Co-authors

Ryan B. Corcoran(13), Yongxin Han(11), Klaus P. Hoeflich(11), Margit Hagel(11), Bradley Quade(10), Brooke M. Swalm(10), Ayşegül Özen(10), Arvin C. Dar(10), Michael Hale(10), Natasha Schenk(9), Zhong Fang(9), Marshall Zingg(9), Steven E. Cohen(9), Chun Li(9), Chaoyang Ye(9), Maria Stella Ritorto(9), Xin Huang(9), Ferran Fece de la Cruz(8), Sarah Phat(8), David T. Myers(8)