Jakob Franke

Leibniz University Hannover — Germany

Medicine · Health Sciences

34h-index3.6kcitations96works3.32yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(16), Cellular Mechanics and Interactions(16), Plant biochemistry and biosynthesis(15), Phosphodiesterase function and regulation(11), Cholinesterase and Neurodegenerative Diseases(8)

Publications96 total

Bioökonomie International 2020: LiMEDisc - Verknüpfung von metabolischem Engineering mit der Identifizierung von Genen zur biotechnologischen Produktion von Camptothecin
TIB Repositorium·2026Open Access
Orthologue inference-based enzyme mining for diversification of the anti-cancer evodiamine scaffold
Communications Chemistry·2026Open Access
Sachbericht
Open MIND·2026
Chemoenzymatic Synthesis with Plant Oxidases and Metabolic Engineering Enable the Total Biosynthesis of Rare Gibberellins
2025Open Access
A plastid carbohydrate carrier mediates ribose recycling from nucleotide catabolism and glucose export from starch degradation
Nature Communications·2025Open Access
Production of the anticancer drug intermediate strictosidinic acid in engineered yeast
2025Open Access
Discovery of corynanthe synthases in Camptotheca acuminata: medium-chain dehydrogenase/reductase-based gateway to corynanthe-type compound diversification
Planta·2025
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
Nature Communications·2025· 12 citedOpen Access
Biochemical breakthrough paves way to reliable supply of anticancer drug
Nature·2025
Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants
Journal of the American Chemical Society·2025· 4 citedOpen Access
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
Leibniz Universität Hannover·2025Open Access
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
2024· 6 citedOpen Access
Chemical tools for unpicking plant specialised metabolic pathways
Current Opinion in Plant Biology·2024· 1 citedOpen Access
Biosynthesis of the allelopathic alkaloid gramine in barley by a cryptic oxidative rearrangement
Science·2024· 26 cited
Chemical tools for unpicking plant specialised metabolic pathways
Leibniz Universität Hannover·2024Open Access
Quassinoide – wie invasive Pflanzen Abwehrstoffe bilden
BIOspektrum·2023Open Access
A New Fluorescence Detection Method for Tryptophan- and Tyrosine-Derived Allelopathic Compounds in Barley and Lupin
Plants·2023· 7 citedOpen Access
Isotope‐Guided Metabolomics Reveals Divergent Incorporation of Valine into Different Flavor Precursor Classes in Chives
ChemBioChem·2023· 2 citedOpen Access
Post-Cyclization Skeletal Rearrangements in Plant Triterpenoid Biosynthesis by a Pair of Branchpoint Isomerases
Journal of the American Chemical Society·2023· 16 citedOpen Access
Leveraging synthetic biology and metabolic engineering to overcome obstacles in plant pathway elucidation
Current Opinion in Plant Biology·2023· 28 cited
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Frequent Co-authors

Richard H. Kessin(22), Christian Hertweck(13), Gregory J. Podgorski(10), Sarah E. O’Connor(6), Michel Faure(6), Keishi Ishida(6), Thu‐Thuy T. Dang(5), Lin Wu(4), Inês Carqueijeiro(3), Vincent Courdavault(3), Evangelos C. Tatsis(3), Martin Baunach(3), Maurice Sussman(3), Felix Trottmann(3), Anne L. Hall(3), Lorenzo Caputi(2), Scott C. Farrow(2), Trinh‐Don Nguyen(2), Thomas Dugé de Bernonville(2), Ivo José Curcino Vieira(2)